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Gene Expression Data
Assay Details
Assay
Reference: J:224948 Lin C, et al., A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7466343
Gene symbol: Pdpn
Gene name: podoplanin
Antibody: Anti-Podoplanin (clone 8.1.1)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Alexa Fluor 594
Results
Specimen 2B: embryonic day 18.5 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 1 cell Present 2B

Specimen 2E: embryonic day 18.5; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 1 cell Present 2E No obvious difference was mentioned.

Specimen 2H: postnatal day 0 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 2H

Specimen 2K: postnatal day 0; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 2K No obvious difference was mentioned.

Specimen 2S: postnatal day 0 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 2S

Specimen 2U: postnatal day 0; Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Tg(Nkx2-1-cre)2Sand/0 (more )
Note: Conditional mutant. Lower lobe of lungs. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 2U No obvious difference was mentioned.

Specimen 2V: postnatal day 0; Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Tg(Nkx2-1-cre)2Sand/0 (more )
Note: Conditional mutant. Upper lobe of lungs. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 2V No obvious difference was mentioned.

Specimen 2X: postnatal day 0; Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Tg(Nkx2-1-cre)2Sand/Tg(Nkx2-1-cre)2Sand (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 2X Positive cells could be readily detected.

Specimen 4D: postnatal day 4 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS28: alveolus epithelium pulmonary alveolar type 1 cell Present 4D

Specimen 4H: postnatal day 4; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Wwtr1tm1.1Eno/Wwtr1+, Yap1tm1.1Eno/Yap1+ (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS28: alveolus epithelium pulmonary alveolar type 1 cell Present 4H Similar as in the control.

Specimen 4L: postnatal day 24 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS28: alveolus epithelium pulmonary alveolar type 1 cell Present 4L

Specimen 4P: postnatal day 24; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Wwtr1tm1.1Eno/Wwtr1+, Yap1tm1.1Eno/Yap1+ (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS28: alveolus epithelium pulmonary alveolar type 1 cell Present 4P Similar as in the control.

Specimen 5D: postnatal day 0 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 5D

Specimen 5H: postnatal day 0; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Yap1tm1.1Eno/Yap1+ (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present 5H Similar as in the control.

Specimen 5L: postnatal day 24 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS28: alveolus epithelium pulmonary alveolar type 1 cell Present 5L

Specimen 5P: postnatal day 24; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Yap1tm1.1Eno/Yap1+ (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS28: alveolus epithelium pulmonary alveolar type 1 cell Present 5P Similar as in the control.

Specimen S3C: embryonic day 18.5 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 1 cell Present S3C

Specimen S3D: embryonic day 18.5; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 1 cell Present S3D No obvious difference was mentioned.

Specimen S3G: postnatal day 0 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present S3G

Specimen S3H: postnatal day 0; Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS27: alveolus epithelium pulmonary alveolar type 1 cell Present S3H No obvious difference was mentioned.

Specimen S3K: embryonic day 18.5 (more )
Note: Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 1 cell Present S3K

Specimen S3L: embryonic day 18.5; Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Tg(Nkx2-1-cre)2Sand/Tg(Nkx2-1-cre)2Sand (more )
Note: Conditional mutant. Double labeled: red - Pdpn; green - Sftpc (assay MGI:7466337).
Structure Cell Type Level Pattern Image Note
TS26: alveolus epithelium pulmonary alveolar type 1 cell Present S3L No obvious difference was mentioned.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory