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Gene Expression Data
Assay Details
Assay
Reference: J:242353 Pichery M, et al., PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. Hum Mol Genet. 2017 May 15;26(10):1787-1800
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7461586
Gene symbol: Ivl
Gene name: involucrin
Antibody: anti-IVL (PRB-140C; Poly19244)
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Fixation was with 4% formalin.
Results
Specimen 2B Involucrin WT: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epidermis Present S4B Involucrin WT
Specimen 2B Involucrin tm1a: embryonic day 18.5; Pnpla1tm1a(KOMP)Wtsi/Pnpla1tm1a(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS26: epidermis Present S4B Involucrin tm1a Authors report no difference compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory