Lipe Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:236180 Zhou H, et al., Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38
Assay type:	Western blot
MGI Accession ID:	MGI:7447319
Gene symbol:	Lipe
Gene name:	lipase, hormone sensitive

Antibody:

anti-phospho-HSL (Ser563) (4139)

Results

Image: 7A pHSL

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
E16.5 +/+	E16.5	TS24: brown fat	Absent	involves: 129S1/Sv * 129X1/SvJ * C57BL/6		Not Specified
E16.5 -/-	E16.5	TS24: brown fat	Absent	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	Bscl2^tm1.1Lchan/Bscl2^tm1.1Lchan	Not Specified
E18.5 +/+	E18.5	TS26: brown fat	Absent	involves: 129S1/Sv * 129X1/SvJ * C57BL/6		Not Specified
E18.5 -/-	E18.5	TS26: brown fat	Trace (a)	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	Bscl2^tm1.1Lchan/Bscl2^tm1.1Lchan	Not Specified
P0 +/+	P0	TS27: brown fat	Present	involves: 129S1/Sv * 129X1/SvJ * C57BL/6		Not Specified
P0 -/-	P0	TS27: brown fat	Present (b)	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	Bscl2^tm1.1Lchan/Bscl2^tm1.1Lchan	Not Specified
P2 +/+	P2	TS27: brown fat	Present	involves: 129S1/Sv * 129X1/SvJ * C57BL/6		Not Specified
P2 -/-	P2	TS27: brown fat	Present (b)	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	Bscl2^tm1.1Lchan/Bscl2^tm1.1Lchan	Not Specified
P5 +/+	P5	TS28: brown fat	Present	involves: 129S1/Sv * 129X1/SvJ * C57BL/6		Not Specified
P5 -/-	P5	TS28: brown fat	Present	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	Bscl2^tm1.1Lchan/Bscl2^tm1.1Lchan	Not Specified

Notes:
(a) Authors report enhanced cAMP/PKA-mediated phosphorylation in late fetal period.
(b) Authors report enhanced cAMP/PKA-mediated phosphorylation in early postnatal period

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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