Ezr Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:237224 Kim JY, et al., Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7437596
Gene symbol:	Ezr
Gene name:	ezrin

Antibody:	anti-ezrin (3C12), (ab4069), (MS-661)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

4C ©

Specimen 4C: embryonic day 16.5; Yap1^tm1.1Eno/Yap1^tm1.1Eno (more

)
Note: Double labeled: green - Ezr; red - Tjp1 (assay MGI:7437598).

Structure	Cell Type	Level	Pattern	Image	Note
TS24: pigmented retinal epithelium	retinal pigment epithelial cell	Present		4C	Preferentially expressed in the apical villi adjacent to outer limiting membrane.

4D ©

Specimen 4D: embryonic day 16.5; Tg(rx3-icre)1Mjam/0, Yap1^tm1.1Eno/Yap1^tm1.1Eno (more

)
Note: Conditional mutant. Double labeled: green - Ezr; red - Tjp1 (assay MGI:7437598).

Structure	Cell Type	Level	Pattern	Image	Note
TS24: pigmented retinal epithelium	retinal pigment epithelial cell	Present	Regionally restricted	4D	The retina-like epithelium lost staining while apical concentration was disrupted and it was broadly localized in the entire cytoplasm in the border cells seeming undergoing transdifferentiation.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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