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Gene Expression Data
Assay Details
Assay
Reference: J:237224 Kim JY, et al., Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437581
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9 (AB5809)
Detection system: Secondary antibody coupled to Cy5
Results
Specimen 1B/C: embryonic day 10.5 (more )
Note: Double labeled: red - Sox9; green - Yap1 (assay MGI:7437575).
Structure Level Pattern Image Note
TS17: diencephalon Present 1C , 1B
TS17: optic stalk Present 1C , 1B
TS17: eye mesenchyme Present Regionally restricted 1C , 1B Expressed in periocular mesenchymal cells.
TS17: optic cup outer layer Present Regionally restricted 1B , 1C Future pigmented retinal epithelium. Coexpressed with Yap1 in a subset of cells.
TS17: neural retinal epithelium Present Regionally restricted 1B , 1C Coexpressed with Yap1 in a subset of cells.
Specimen 2E/F: embryonic day 15.5 (more )
Note: Double labeled: red - Sox9; green - Yap1 (assay MGI:7437575).
Structure Level Pattern Image Note
TS23: neural retina Present 2E , 2F
TS23: pigmented retinal epithelium Present 2E , 2F
Specimen S4E: postnatal day 0; Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Double labeled: red - Sox9; green - Yap1 (assay MGI:7437575).
Structure Cell Type Level Pattern Image Note
TS27: neural retina retinal progenitor cell Present Regionally restricted S4E Expressed in the outer neuroblastic layer.
Specimen S4F: postnatal day 0; Tg(rx3-icre)1Mjam/0, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Double labeled: red - Sox9; green - Yap1 (assay MGI:7437575).
Structure Cell Type Level Pattern Image Note
TS27: neural retina retinal progenitor cell Present Regionally restricted S4F Expressed in the outer neuroblastic layer, similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory