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Gene Expression Data
Assay Details
Assay
Reference: J:283394 Hughes LJ, et al., Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7435352
Gene symbol: Crb2
Gene name: crumbs family member 2
Antibody: anti-pan-Crb
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The specificity of the antibody used was not detailed; all family members have been annotated.
Results
Specimen S7C/C': embryonic day 16.5 (more )
Note: Double labeled: green - Crbs; red - Cdh2 (assay MGI:7434611).
Structure Cell Type Level Pattern Image Note
TS24: cerebellum ventricular layer neuroepithelial stem cell Present Regionally restricted S7C' , S7C Expressed in the apical junctional complex of neuroepithelium at the ventricular surface continuously.

Specimen S7D/D': embryonic day 16.5; Tg(GFAP-cre)25Mes/0, Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Double labeled: green - Crbs; red - Cdh2 (assay MGI:7434611).
Structure Cell Type Level Pattern Image Note
TS24: cerebellum ventricular layer neuroepithelial stem cell Present Regionally restricted S7D , S7D' Not expressed at the ventricular surface in some areas.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory