Sox10 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:333013 Huang T, et al., Direct Interaction of Sox10 With Cadherin-19 Mediates Early Sacral Neural Crest Cell Migration: Implications for Enteric Nervous System Development Defects. Gastroenterology. 2022 Jan;162(1):179-192.e11
Assay type:	RNA in situ
MGI Accession ID:	MGI:7434137
Gene symbol:	Sox10
Gene name:	SRY (sex determining region Y)-box 10

Probe:	Sox10 probe34
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen S5A +/+ Sox10: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		S5A +/+ Sox10

Specimen S5A Dom/Dom Sox10: embryonic day 9.5; Sox10^Dom/Sox10^Dom (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Weak		S5A Dom/Dom Sox10	Expression decreased compared to wildtype.

S5Biv ©

S5Bv ©

S5Bvi ©

Specimen S5B +/+ Sox10: embryonic day 10.5 (more

)

Structure	Level	Image
TS17: facial ganglion	Present	S5Bv , S5Biv
TS17: trigeminal ganglion	Present	S5Bv , S5Biv
TS17: dorsal root ganglion	Present	S5Biv , S5Bvi

S5Civ ©

S5Cv ©

S5Cvi ©

Specimen S5B Dom/Dom Sox10: embryonic day 10.5; Sox10^Dom/Sox10^Dom (more

)

Structure	Level	Image	Note
TS17: facial ganglion	Weak	S5Civ , S5Cv	Expression down-regulated in trigeminal and facial ganglia.
TS17: trigeminal ganglion	Weak	S5Civ , S5Cv	Expression down-regulated in trigeminal and facial ganglia.
TS17: dorsal root ganglion	Present	S5Civ , S5Cvi	Expression remains in dorsal root ganglion.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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