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Gene Expression Data
Assay Details
Assay
Reference: J:332853 Castilla-Ibeas A, et al., Failure of digit tip regeneration in the absence of Lmx1b suggests Lmx1b functions disparate from dorsoventral polarity. Cell Rep. 2023 Jan 13;42(1):111975
Assay type: RNA in situ
MGI Accession ID: MGI:7432715
Gene symbol: Lmx1b
Gene name: LIM homeobox transcription factor 1 beta
Probe: Lmx1b probe16
Probe preparation: Antisense labelled with Alexa Fluor 647 RNA
Results
Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Strong Regionally restricted 3A inset , 3A Robust expression in dorsal msoderm.
Specimen 3A': embryonic day 11.5; Del(1)1Smun/Del(1)1Smun, Del(2Rr263-Rr265)1Kco/Del(2Rr263-Rr265)1Kco (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Absent 3A' , 3A' inset
Specimen 3B: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: hindlimb digit skin Weak Regionally restricted 3B inset , 3B Decreased expression in dorsal dermis.
Specimen 3B': postnatal day 3; Del(1)1Smun/Del(1)1Smun, Del(2Rr263-Rr265)1Kco/Del(2Rr263-Rr265)1Kco (more )
Structure Level Pattern Image Note
TS27: hindlimb digit skin Absent 3B' , 3B' inset
Specimen 3E: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: dermis Trace Regionally restricted 3E Expression in dorsal dermis further decreased but still detectable.
Specimen 3F: postnatal day 21; Del(1)1Smun/Del(1)1Smun, Del(2Rr263-Rr265)1Kco/Del(2Rr263-Rr265)1Kco (more )
Structure Level Pattern Image Note
TS28: dermis Absent 3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory