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Gene Expression Data
Assay Details
Assay
Reference: J:199435 Barraud P, et al., Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7427801
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Reporter: lacZ
Antibody: anti-B-galactosidase (Abcam)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2A: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: Parasagittal section. Double labeled: magenta - Sox10 reporter; green - Tubb3 (assay MGI:7427814).
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve neural crest cell Present 2A2 , 2A3 , 2A , 2A1 Expression is seen in neural crest-derived cells associated with the olfactory nerve.
TS20: head mesenchyme Present Regionally restricted 2A1 , 2A Expression is seen in mesenchymal cells beneath the olfactory epithelium; it is believed these are neural crest-derived cells.
Specimen 2B: embryonic day 12.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: Parasagittal section. Double labeled: magenta - Sox10 reporter; green - Tubb3 (assay MGI:7427814).
Structure Cell Type Level Pattern Image Note
TS21: olfactory nerve neural crest cell Present 2B1 , 2B Expression is seen in neural crest-derived cells associated with the olfactory nerve.
Specimen 2C: embryonic day 16.5; Sox10tm1Weg/Sox10+ (more )
Note: Coronal section. Double labeled: magenta - Sox10 reporter; green - Tubb3 (assay MGI:7427814).
Structure Cell Type Level Pattern Image Note
TS24: nasal cavity lamina propria neural crest cell Present 2C1 , 2C Expressing cells are distributed along the olfactory nerve from the lamina propria to the olfactory nerve layer of the olfactory bulb.
TS24: main olfactory bulb olfactory nerve layer neural crest cell Present 2C , 2C2 Expressing cells are distributed along the olfactory nerve from the lamina propria to the olfactory nerve layer of the olfactory bulb.
TS24: olfactory nerve neural crest cell Present 2C , 2C2 Expressing cells are distributed along the olfactory nerve from the lamina propria to the olfactory nerve layer of the olfactory bulb.
TS24: gland Present Regionally restricted 2C1 , 2C Expression is seen in the developing Bowman's gland.
TS24: ethmoid bone cribriform plate Weak 2C , 2C1
TS24: nasal septum cartilage Weak 2C , 2C1
Specimen 2D: embryonic day 16.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: Coronal section. Double labeled: magenta - Sox10 reporter; green - Tubb3 (assay MGI:7427814).
Structure Cell Type Level Pattern Image Note
TS24: nasal cavity lamina propria neural crest cell Absent 2D1 , 2D Expressing cells are seen along the proximal part of the olfactory nerve, near its entry point into the olfactory bulb, but not in the lamina propria.
TS24: main olfactory bulb olfactory nerve layer neural crest cell Present 2D2 , 2D Expressing cells are seen along the proximal part of the olfactory nerve, near its entry point into the olfactory bulb, but not in the lamina propria.
TS24: olfactory nerve neural crest cell Present 2D2 , 2D Expressing cells are seen along the proximal part of the olfactory nerve, near its entry point into the olfactory bulb, but not in the lamina propria.
TS24: gland Present Regionally restricted 2D , 2D1 Expression is seen in the developing Bowman's gland.
TS24: ethmoid bone cribriform plate Weak 2D
TS24: nasal septum cartilage Weak 2D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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