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Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7425000
Gene symbol: Hey2
Gene name: hairy/enhancer-of-split related with YRPW motif 2
Probe: Hey2 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7 - Hey2: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread 7c , 7b The ONL-OECs show expression.
TS24: olfactory nerve olfactory ensheathing cell Present 7b , 7d The mucosal OECs show expression.
TS24: trigeminal nerve Schwann cell Absent 7b , 7e The Schwann cells lack expression.

Specimen 9 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Present 9b , 9c The mucosal OECs show expression.

Specimen 9 - E13.5: embryonic day 13.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS22: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present 9d , 9e The ONL-OECs show expression.
TS22: olfactory nerve olfactory ensheathing cell Present 9f , 9d The mucosal OECs show expression.

Specimen 12k: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread 12k1 , 12k The ONL-OECs show expression.

Specimen 12l: embryonic day 16.5; Ptprz1tm1Mno/Ptprz1tm1Mno (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread 12l , 12l1 The ONL-OECs show expression. Expression levels in the mutant are much higher than those seen in wild type.

Specimen 12m: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present 12m1 , 12m The mucosal OECs show expression.

Specimen 12n: embryonic day 16.5; Ptprz1tm1Mno/Ptprz1tm1Mno (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present 12n1 , 12n The mucosal OECs show expression. Expression levels in the mutant are much higher than those seen in wild type.

Specimen S14E: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread S14E , S14E1 The ONL-OECs show expression.

Specimen S14F: embryonic day 16.5; Ptntm1Tmu/Ptntm1Tmu (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Widespread S14F , S14F1 The ONL-OECs show expression. Expression levels in the mutant are comparable to those seen in wild type.

Specimen S14G: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present S14G1 , S14G The mucosal OECs show expression.

Specimen S14H: embryonic day 16.5; Ptntm1Tmu/Ptntm1Tmu (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: olfactory nerve olfactory ensheathing cell Present S14H1 , S14H The mucosal OECs show expression. Expression levels in the mutant are comparable to those seen in wild type.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory