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Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7424937
Gene symbol: Nkd2
Gene name: naked cuticle 2
Probe: Nkd2 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3 - Nkd2: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform 3k , 3j The inner ONL-OECs show strong expression, the outer ONL-OECs weaker expression.
TS24: olfactory nerve olfactory ensheathing cell Absent 3j , 3l The mucosal OECs lack expression.
TS24: head mesenchyme Strong Regionally restricted 3l , 3j Strong expression is seen near the olfactory epithelium.
TS24: trigeminal nerve Schwann cell Absent 3j , 3m The Schwann cells lack expression.
Specimen S11 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Absent S11B , S11C The mucosal OECs lack expression.
Specimen S11 - E13 - D1: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: main olfactory bulb layer olfactory ensheathing cell Absent S11D1 , S11E1 The olfactory nerve layer OECs lack expression.
Specimen S11 - E13 - D2: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: olfactory nerve olfactory ensheathing cell Absent S11E2 , S11D2 The mucosal OECs lack expression.
Specimen S13E: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S13E1 , S13E The inner ONL-OECs show strong expression, the outer ONL-OECs weaker expression.
Specimen S13F: embryonic day 16.5; Ptprz1tm1Mno/Ptprz1tm1Mno (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S13F1 , S13F The inner ONL-OECs show strong expression, the outer ONL-OECs weaker expression. Expression levels in the mutant are comparable to those seen in wild type.
Specimen S14M: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S14M1 , S14M The inner ONL-OECs show strong expression, the outer ONL-OECs weaker expression.
Specimen S14N: embryonic day 16.5; Ptntm1Tmu/Ptntm1Tmu (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Strong Non-Uniform S14N1 , S14N The inner ONL-OECs show strong expression, the outer ONL-OECs weaker expression. Expression levels in the mutant are comparable to those seen in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory