About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:235128 Katayama Y, et al., CHD8 haploinsufficiency results in autistic-like phenotypes in mice. Nature. 2016 Sep 29;537(7622):675-679
Assay type: Western blot
MGI Accession ID: MGI:7413081
Gene symbol: Chd8
Gene name: chromodomain helicase DNA binding protein 8
Antibody: anti-pan-CHD8
Results Image: 1a
 Sample Information Bands Other Sample Information
Lane AgeStructure 280 kDa (a) Genetic BackgroundMutant Allele(s)Sex
E10.5 WB +/+ E10.5 TS17: brain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
E10.5 WB +/deltaSL E10.5 TS17: brain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
E10.5 WB +/+ E10.5 TS17: brain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
E10.5 WB +/deltaL E10.5 TS17: brain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
E14.5 WB +/+ E14.5 TS22: brain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
E14.5 WB +/deltaSL E14.5 TS22: brain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
E14.5 WB +/+ E14.5 TS22: brain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
E14.5 WB +/deltaL E14.5 TS22: brain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
E18.5 WB +/+ E18.5 TS26: brain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
E18.5 WB +/deltaSL E18.5 TS26: brain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
E18.5 WB +/+ E18.5 TS26: brain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
E18.5 WB +/deltaL E18.5 TS26: brain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
OB +/+ P w 9 TS28: main olfactory bulb Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
OB +/deltaSL P w 9 TS28: main olfactory bulb Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
OB +/+ P w 9 TS28: main olfactory bulb Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
OB +/deltaL P w 9 TS28: main olfactory bulb Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
CTX +/+ P w 9 TS28: cerebral cortex Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
CTX +/deltaSL P w 9 TS28: cerebral cortex Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
CTX +/+ P w 9 TS28: cerebral cortex Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
CTX +/deltaL P w 9 TS28: cerebral cortex Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
HIP +/+ P w 9 TS28: hippocampus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
HIP +/deltaSL P w 9 TS28: hippocampus Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
HIP +/+ P w 9 TS28: hippocampus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
HIP +/deltaL P w 9 TS28: hippocampus Present involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
STR +/+ P w 9 TS28: corpus striatum Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
STR +/deltaSL P w 9 TS28: corpus striatum Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
STR +/+ P w 9 TS28: corpus striatum Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
STR +/deltaL P w 9 TS28: corpus striatum Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
TH +/+ P w 9 TS28: thalamus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
TH +/deltaSL P w 9 TS28: thalamus Present involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
TH +/+ P w 9 TS28: thalamus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
TH +/deltaL P w 9 TS28: thalamus Present involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
HY +/+ P w 9 TS28: hypothalamus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
HY +/delta SL P w 9 TS28: hypothalamus Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
HY +/+ P w 9 TS28: hypothalamus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
HY +/deltaL P w 9 TS28: hypothalamus Weak (b) involves: 129P2/OlaHsd * C57BL/6J Not Specified
MB +/+ P w 9 TS28: midbrain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
MB +/deltaSL P w 9 TS28: midbrain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
MB +/+ P w 9 TS28: midbrain Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
MB +/deltaL P w 9 TS28: midbrain Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
CB +/+ P w 9 TS28: cerebellum Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
CB +/deltaSL P w 9 TS28: cerebellum Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
CB +/+ P w 9 TS28: cerebellum Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
CB +/deltaL P w 9 TS28: cerebellum Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
P +/+ P w 9 TS28: pons Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
P +/deltaSL P w 9 TS28: pons Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
P +/+ P w 9 TS28: pons Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
P +/deltaL P w 9 TS28: pons Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
Notes:
(a) CHD8L
(b) Level of expression was ~50-70% that of wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory