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Gene Expression Data
Assay Details
Assay
Reference: J:331474 Krueger LA, et al., Chromatin remodeler Chd7 regulates photoreceptor development and outer segment length. Exp Eye Res. 2022 Nov 4;226:109299
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7397299
Gene symbol: Chd7
Gene name: chromodomain helicase DNA binding protein 7
Antibody: anti-Chd7 (D3F5; #6505)
Detection system: Secondary antibody
Results
Specimen 2A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: neural retina Strong Regionally restricted 2A Expression is seen in the inner neuroblastic layer.

Specimen 2B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: retina ganglion cell layer Present 2B
TS26: retina inner nuclear layer Present 2B Expression is seen in the inner neuroblastic layer.
TS26: retina outer nuclear layer Present Single cells 2B Sporadic expression is seen in the outer neuroblastic layer.

Specimen 2C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Strong 2C
TS27: retina inner nuclear layer Strong 2C
TS27: retina outer nuclear layer Strong 2C

Specimen 2D: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Strong 2D
TS28: retina inner nuclear layer Strong Regionally restricted 2D Expression is seen in inner cells of the inner nuclear layer.
TS28: retina outer nuclear layer Absent 2D

Specimen 2E: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Strong 2E
TS28: retina inner nuclear layer Strong Regionally restricted 2E Expression is seen in inner cells of the inner nuclear layer.
TS28: retina outer nuclear layer Weak Single cells 2E

Specimen 2F: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Strong 2F
TS28: retina inner nuclear layer Strong 2F
TS28: retina outer nuclear layer Strong Regionally restricted 2F Expression is seen in a band of cells in the distal outer nuclear layer.

Specimen 2G: embryonic day 15.5; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS23: neural retina Weak 2G Expression is significantly decreased in the mutant.

Specimen 2H: postnatal day 15; Chd7Gt(S20-7E1)Sor/Chd7+ (more )
Structure Level Pattern Image Note
TS28: neural retina Weak 2H Expression is significantly decreased in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory