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Gene Expression Data
Assay Details
Assay
Reference: J:324175 Su YC, et al., YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex. Dev Dyn. 2022 May;251(5):846-863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378739
Gene symbol: Satb2
Gene name: special AT-rich sequence binding protein 2
Antibody: anti-SATB2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2K: postnatal day 0; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Structure Level Pattern Image Note
TS27: cortical layer II Present 2K Expressing cells distributed in upper layers.
TS27: cortical layer III Present 2K Expressing cells distributed in upper layers.
TS27: cortical layer IV Present 2K Expressing cells distributed in upper layers.
Specimen 2L: postnatal day 0; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cortical layer II Weak 2L Expressing cells reduced compared to controls.
TS27: cortical layer III Weak 2L Expressing cells reduced compared to controls.
TS27: cortical layer IV Weak 2L Expressing cells reduced compared to controls.
Specimen 3E.E': postnatal day 0; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Double labeled: green - Satb2; red - EdU.
Structure Level Pattern Image Note
TS27: cortical layer II Present 3E , 3E' Expressing cells distributed in upper layers.
TS27: cortical layer III Present 3E , 3E' Expressing cells distributed in upper layers.
TS27: cortical layer IV Present 3E , 3E' Expressing cells distributed in upper layers.
Specimen 3F,F': postnatal day 0; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant. Double labeled: green - Satb2; red - EdU.
Structure Level Pattern Image Note
TS27: cortical layer II Weak 3F , 3F' Expressing cells reduced compared to controls.
TS27: cortical layer III Weak 3F , 3F' Expressing cells reduced compared to controls.
TS27: cortical layer IV Weak 3F , 3F' Expressing cells reduced compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory