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Gene Expression Data
Assay Details
Assay
Reference: J:137010 Petrou P, et al., Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome. J Biol Chem. 2005 Mar 18;280(11):10350-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7377697
Gene symbol: Nid1
Gene name: nidogen 1
Antibody: anti-Nidogen-1
Detection system: Secondary antibody
Results
Specimen 3A: embryonic day 14.5 (more )
Note: Specimen was the dorsal part of the left lung.
Structure Level Pattern Image Note
TS22: basement membrane of epithelium Present Regionally restricted 3A Expression is in the basement membrane of the visceral pleura and conducting airways.
TS22: visceral pleura Present Regionally restricted 3A Expression is in the basement membrane of the visceral pleura and conducting airways.
TS22: lung mesenchyme Present 3A

Specimen 3B: embryonic day 14.5; Fras1tm1Chpk/Fras1tm1Chpk (more )
Note: Specimen was the dorsal part of the left lung.
Structure Level Pattern Image Note
TS22: basement membrane of epithelium Weak Regionally restricted 3B Expression is in the basement membrane of the visceral pleura and conducting airways. The reduction was more pronounced in the visceral pleura basement membrane.
TS22: visceral pleura Weak Regionally restricted 3B Expression is in the basement membrane of the visceral pleura and conducting airways. The reduction was more pronounced in the visceral pleura basement membrane.
TS22: lung mesenchyme Weak 3B

Specimen 3E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: basement membrane of epithelium Present Regionally restricted 3E Expression is in the skin basement membrane.
TS22: epidermis Present Regionally restricted 3E Expression is in the skin basement membrane.

Specimen 3F: embryonic day 14.5; Fras1tm1Chpk/Fras1tm1Chpk (more )
Structure Level Pattern Image Note
TS22: basement membrane of epithelium Present Regionally restricted 3F In this mutant expression is in the skin basement membrane is the same as in wild-type.
TS22: epidermis Present Regionally restricted 3F In this mutant expression is in the skin basement membrane is the same as in wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory