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Gene Expression Data
Assay Details
Assay
Reference: J:116586 Li H, et al., Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning. Mol Cell Neurosci. 2006 Oct;33(2):136-49
Assay type: RNA in situ
MGI Accession ID: MGI:7367164
Gene symbol: Cdk4
Gene name: cyclin dependent kinase 4
Probe: Cdk4 cDNA3
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 3C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Strong 3C Expression is uniform in proliferating cortical precursor cells.
TS23: cerebral cortex ventricular layer Strong 3C Expression is uniform in proliferating cortical precursor cells.
TS23: corpus striatum Present Regionally restricted 3C Expression is in proliferating striatal precursor cells.
TS23: hippocampus Present 3C

Specimen 3C': embryonic day 15.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Weak Regionally restricted 3C' There is some expression in the most caudal area.
TS23: cerebral cortex ventricular layer Weak Regionally restricted 3C' There is some expression in the most caudal area.
TS23: hippocampus Weak Regionally restricted 3C' There is some expression in the most caudal area.

Specimen 4C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Strong 4C
TS26: cortical plate Weak Single cells 4C Traces of expression were seen in postmitotic cells.

Specimen 4C': embryonic day 18.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Weak Diffuse 4C' Expression in this mutant is more diffused and broader compared to wild-type.
TS26: cerebral cortex Weak 4C'

Specimen 4D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Strong 4D
TS26: cortical plate Weak Single cells 4D Traces of expression were seen in postmitotic cells.

Specimen 4D': embryonic day 18.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Weak 4D' The expression area in this mutant is thinner compared to wild-type.
TS26: cerebral cortex Weak 4D'


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory