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Gene Expression Data
Assay Details
Assay
Reference: J:192973 Kawamura I, et al., SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-beta and bone morphogenetic protein pathways. J Biol Chem. 2012 Aug 17;287(34):29101-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343847
Gene symbol: Smad2
Gene name: SMAD family member 2
Antibody: anti-phospho-Smad2 (3103)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The antibody used recognizes the phosphorylated form of the protein.
Results
Specimen 3D: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: epiphyseal plate proliferative zone growth plate cartilage chondrocyte Present 3D p-Smad2 Expressed in some of the proliferative chondrocytes.
TS25: epiphyseal plate hypertrophic zone Present Regionally restricted 3D p-Smad2 Expressed in most of the prehypertrophic chondrocytes. Not phosphorylated in hypertrophic chondrocytes.
TS25: epiphyseal plate hypertrophic zone hypertrophic chondrocyte Absent 3D p-Smad2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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