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Gene Expression Data
Assay Details
Assay
Reference: J:239360 Zhang Y, et al., Dynamic expression of Lgr6 in the developing and mature mouse cochlea. Front Cell Neurosci. 2015;9:165
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7335961
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin 7a
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 1B E15.5 Apical: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1B-1-3 , 1B-1-5 Expressed in the base of the organ of Corti.
Specimen 1B E15.5 Middle: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1B-2-5 , 1B-2-3 Expressed in the base of the organ of Corti.
Specimen 1B E15.5 Basal: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1B-3-3 , 1B-3-5 Expressed in the base of the organ of Corti.
Specimen 1B E18.5 Apical: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 1B-4-5 , 1B-4-3
TS26: cochlear duct epithelium cochlear outer hair cell Present 1B-4-5 , 1B-4-3
TS26: organ of Corti cochlear inner hair cell Present 1B-4-5 , 1B-4-3
TS26: organ of Corti cochlear outer hair cell Present 1B-4-5 , 1B-4-3
Specimen 1B E18.5 Middle: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 1B-5-5 , 1B-5-3
TS26: cochlear duct epithelium cochlear outer hair cell Present 1B-5-5 , 1B-5-3
TS26: organ of Corti cochlear inner hair cell Present 1B-5-5 , 1B-5-3
TS26: organ of Corti cochlear outer hair cell Present 1B-5-5 , 1B-5-3
Specimen 1B E18.5 Basal: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 1B-6-3 , 1B-6-5
TS26: cochlear duct epithelium cochlear outer hair cell Present 1B-6-3 , 1B-6-5
TS26: organ of Corti cochlear inner hair cell Present 1B-6-3 , 1B-6-5
TS26: organ of Corti cochlear outer hair cell Present 1B-6-3 , 1B-6-5
Specimen 2A E15.5 Apical: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlear inner hair cell Present Regionally restricted 2A-1-2 , 2A-1-5 Expressed in the middle and basal turns. No expression in the apical turn.
TS23: cochlear duct epithelium cochlear outer hair cell Present Regionally restricted 2A-1-2 , 2A-1-5 Expressed in the middle and basal turns. No expression in the apical turn.
Specimen 2A E15.5 Middle: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlear inner hair cell Present 2A-2-2 , 2A-2-5
TS23: cochlear duct epithelium cochlear outer hair cell Present 2A-2-2 , 2A-2-5
Specimen 2A E15.5 Basal: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlear inner hair cell Present 2A-3-2 , 2A-3-5
TS23: cochlear duct epithelium cochlear outer hair cell Present 2A-3-2 , 2A-3-5
Specimen 2A E18.5 Apical: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2A-4-5 , 2A-4-2
TS26: cochlear duct epithelium cochlear outer hair cell Present 2A-4-5 , 2A-4-2
Specimen 2A E18.5 Middle: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2A-5-5 , 2A-5-2
TS26: cochlear duct epithelium cochlear outer hair cell Present 2A-5-5 , 2A-5-2
Specimen 2A E18.5 Basal: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2A-6-5 , 2A-6-2
TS26: cochlear duct epithelium cochlear outer hair cell Present 2A-6-5 , 2A-6-2
Specimen 3D section Apical: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3D-1-3 , 3D-1-5
TS27: cochlear duct epithelium cochlear outer hair cell Present 3D-1-3 , 3D-1-5
Specimen 3D section Middle: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3D-2-5 , 3D-2-3
TS27: cochlear duct epithelium cochlear outer hair cell Present 3D-2-5 , 3D-2-3
Specimen 3D section Basal: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3D-3-5 , 3D-3-3
TS27: cochlear duct epithelium cochlear outer hair cell Present 3D-3-5 , 3D-3-3
Specimen 3D wholemount Apical: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3D-4-5 , 3D-4-3
TS27: cochlear duct epithelium cochlear outer hair cell Present 3D-4-5 , 3D-4-3
Specimen 3D wholemount Middle: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3D-5-5 , 3D-5-3
TS27: cochlear duct epithelium cochlear outer hair cell Present 3D-5-5 , 3D-5-3
Specimen 3D wholemount Basal: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3D-6-5 , 3D-6-3
TS27: cochlear duct epithelium cochlear outer hair cell Present 3D-6-5 , 3D-6-3
Specimen 4 Apical P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 4_Apical-4
TS28: cochlear duct epithelium cochlear outer hair cell Present 4_Apical-4
Specimen 4 Middle P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 4_Middle-4
TS28: cochlear duct epithelium cochlear outer hair cell Present 4_Middle-4
Specimen 4 Basal P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 4_Basal-4
TS28: cochlear duct epithelium cochlear outer hair cell Present 4_Basal-4
Specimen 6A P20 upper: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6A-1-3 , 6A-1-5
TS28: cochlear duct epithelium cochlear outer hair cell Present 6A-1-3 , 6A-1-5
Specimen 6A P20 lower: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6A-2-5 , 6A-2-3
TS28: cochlear duct epithelium cochlear outer hair cell Present 6A-2-5 , 6A-2-3
Specimen 6A P30: postnatal day 30; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6A-3-5 , 6A-3-3
TS28: cochlear duct epithelium cochlear outer hair cell Present 6A-3-5 , 6A-3-3
Specimen S1 Apical: postnatal day 3; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present S1_Apical-3 , S1_Apical-5
TS27: cochlear duct epithelium cochlear outer hair cell Present S1_Apical-3 , S1_Apical-5
Specimen S1 Middle: postnatal day 3; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present S1_Middle-5 , S1_Middle-3
TS27: cochlear duct epithelium cochlear outer hair cell Present S1_Middle-5 , S1_Middle-3
Specimen S1 Basal: postnatal day 3; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: white - Myo7a; red - Sox2 (assay MGI:7335247); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present S1_Basal-3 , S1_Basal-5
TS27: cochlear duct epithelium cochlear outer hair cell Present S1_Basal-3 , S1_Basal-5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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