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Gene Expression Data
Assay Details
Assay
Reference: J:302139 Ramirez-Martinez A, et al., The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. Nat Commun. 2021 Jan 29;12(1):690
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7331403
Gene symbol: Sun2
Gene name: Sad1 and UNC84 domain containing 2
Antibody: anti-SUN2 (clone 3.1E) (MABT880)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2b WT: postnatal day 17 (more )
Note: Double labeled: red - Sun2; green - phalloidin.
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 2b WT Expression in inner nuclear membrane.
Specimen 2b KO: postnatal day 17; Plpp7em1Eno/Plpp7em1Eno (more )
Note: Double labeled: red - Sun2; green - phalloidin.
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 2b KO Authors report nuclear envelope deformations charcterized by pronounced invaginations and projections protruding into sarcomeres.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory