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Gene Expression Data
Assay Details
Assay
Reference: J:326587 Hurley S, et al., Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development. Mol Autism. 2021 Feb 24;12(1):16
Assay type: Western blot
MGI Accession ID: MGI:7316751
Gene symbol: Chd8
Gene name: chromodomain helicase DNA binding protein 8
Antibody: anti-Chd8 (#A301-224A)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Image: 1c ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
+/+ E12.5 TS20: neocortex Present involves: C57BL/6J Not Specified
+/- E12.5 TS20: neocortex Weak (a) involves: C57BL/6J Chd8tm1.2Mabn/Chd8+Not Specified
neo/neo E12.5 TS20: neocortex Weak (b) involves: C57BL/6J Chd8tm1Mabn/Chd8tm1MabnNot Specified
neo/- E12.5 TS20: neocortex Trace (c) involves: C57BL/6J Chd8tm1Mabn/Chd8tm1.2MabnNot Specified
Notes:
(a) Expression reduced 50% compared to wild type.
(b) Expression reduced 64% compared to wild type.
(c) Expression reduced 91% compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory