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Gene Expression Data
Assay Details
Assay
Reference: J:173286 Long JE, et al., Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
Assay type: RNA in situ
MGI Accession ID: MGI:7316420
Gene symbol: Pbx3
Gene name: pre B cell leukemia homeobox 3
Probe: Pbx3 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1QQ: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: globus pallidus Present 1QQ
TS23: lateral ganglionic eminence Present 1QQ
TS23: medial ganglionic eminence Weak 1QQ
Specimen 1QQ': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1QQ'
TS23: globus pallidus Present Regionally restricted 1QQ' In this mutant the globus pallidus is smaller with a reduced number of expressing neurons.
TS23: medial ganglionic eminence Present Regionally restricted 1QQ' In this mutant expression increased in the mantle zone.
Specimen 1RR: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1RR
Specimen 1RR': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1RR' Expression is reduced in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory