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Gene Expression Data
Assay Details
Assay
Reference: J:171508 Ikegami D, et al., Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
Assay type: RNA in situ
MGI Accession ID: MGI:7287468
Gene symbol: Col11a2
Gene name: collagen, type XI, alpha 2
Probe: Col11a2 probe1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen S4A Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation chondrocyte Present Regionally restricted S4A Col11a2 Sox9flox/+ Expression corresponded to that of Sox9 - which was detected in ephiphyseal round chondrocytes and metaphyseal flat chondrocytes.
Specimen S4A 11Prom-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation chondrocyte Present Regionally restricted S4A Col11a2 11Prom-Cre;Sox9flox/flox Expression corresponded to that of Sox9 - which was only detected in ephiphyseal round chondrocytes in the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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