Gene Expression Data
Assay Details
Assay
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Reference:
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J:168841
Lopes Floro K, et al., Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis. Hum Mol Genet. 2011 Mar 15;20(6):1097-110
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7286315
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Gene symbol:
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Pitx2
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Gene name:
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paired-like homeodomain transcription factor 2
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Probe:
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Pitx2 probe35
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3A:
embryonic day 9.5; Mesp1tm2(cre)Ysa/Mesp1 +
(more )
Note: Conditional mutant.
Specimen
3A:
(close )
Genetic Background:
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involves: C57BL/6J * C57BL/6N * CBA
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Mutant Allele(s):
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Mesp1tm2(cre)Ysa/Mesp1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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Conditional mutant.
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Specimen
3B:
(close )
Specimen
3C:
embryonic day 9.5; Mesp1tm2(cre)Ysa/Mesp1 +
(more )
Note: Conditional mutant.
Specimen
3C:
(close )
Genetic Background:
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involves: C57BL/6J * C57BL/6N * CBA
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Mutant Allele(s):
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Mesp1tm2(cre)Ysa/Mesp1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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Specimen
3D:
(close )
Genetic Background:
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involves: 129 * C57BL/6J * C57BL/6N * CBA
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1.1Dunw Mesp1tm2(cre)Ysa/Mesp1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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Specimen
3E:
embryonic day 9.5; Tg(Leftb-cre)1Hmd/0
(more )
Note: Conditional mutant.
Specimen
3E:
(close )
Genetic Background:
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involves: 129 * C3H * C57BL/6J
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Mutant Allele(s):
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Tg(Leftb-cre)1Hmd/0
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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Conditional mutant.
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Specimen
3F:
(close )
Specimen
3G:
embryonic day 9.5; Tg(Leftb-cre)1Hmd/0
(more )
Note: Conditional mutant.
Specimen
3G:
(close )
Genetic Background:
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involves: 129 * C3H * C57BL/6J
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Mutant Allele(s):
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Tg(Leftb-cre)1Hmd/0
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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Specimen
3H:
(close )
Specimen
3I:
embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1 +
(more )
Note: Conditional mutant.
Specimen
3I:
(close )
Genetic Background:
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involves: C57BL/6J * C57BL/6N * CBA
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Mutant Allele(s):
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Mesp1tm2(cre)Ysa/Mesp1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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Conditional mutant.
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Structure |
Level |
Pattern |
Image |
Note |
TS17: heart |
Present |
Regionally restricted |
3I
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Expression in heart including outflow tract.
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TS17: outflow tract |
Present |
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3I
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Specimen
3J:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS17: heart |
Present |
Regionally restricted |
3J
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Expression in heart including outflow tract.
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TS17: outflow tract |
Present |
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3J
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Specimen
5A:
embryonic day 9.5
(more )
Specimen
5A:
(close )
Genetic Background:
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involves: 129 * C57BL/6J
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Age:
|
embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5B:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5C:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * Swiss
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb Smad1tm1Rob/Smad1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS15: mesenchyme derived from lateral plate |
Present |
Regionally restricted |
5C
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Expression on left side within pericardio-peritoneal canal and lateral mesoderm in some mutant embryos.
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TS15: pericardio-peritoneal canal |
Present |
Regionally restricted |
5C
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Expression on left side within pericardio-peritoneal canal and lateral mesoderm in some mutant embryos.
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Specimen
5D:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * Swiss
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb Smad1tm1Rob/Smad1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5E:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * Swiss
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb Smad1tm1Rob/Smad1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5F:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5G:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * Swiss
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb Smad1tm1Rob/Smad1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5H:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * Swiss
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb Smad1tm1Rob/Smad1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS15: dorsal mesocardium |
Strong |
Regionally restricted |
5H
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Strong bilateral expression in lung bud and dorsal mesocardium.
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TS15: lung |
Strong |
Regionally restricted |
5H
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Strong bilateral expression in lung bud and dorsal mesocardium.
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Specimen
5I:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * Swiss
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb Smad1tm1Rob/Smad1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS15: lung |
Weak |
Regionally restricted |
5I
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Weak left-sided lung bud expression.
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Specimen
5J:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * Swiss
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb Smad1tm1Rob/Smad1+
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Age:
|
embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: lung |
Strong |
Regionally restricted |
5J
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Strong left-sided lung bud expression.
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