Gene Expression Data
Assay Details
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Assay
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Reference:
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J:321982
De A, et al., The beta8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development. Development. 2022 Mar 15;149(6):dev200472
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7282033
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Gene symbol:
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Gfap
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Gene name:
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glial fibrillary acidic protein
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Antibody:
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Anti-GFAP
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Assay notes:
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The antibody used in this assay was not specified; two antibodies were listed: MGI:1314977 and MGI:7281834.
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Results
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Specimen
S8A:
postnatal day 60
(more  )
Specimen
S8A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 60
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S8C:
(close )
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Genetic Background:
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either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6J)
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Mutant Allele(s):
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Itgb8tm1Lfr/Itgb8tm1Lfr
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Age:
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postnatal day 60
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
astrocyte of the cerebral cortex |
Present |
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S8C
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Increased numbers of astrocytes were noted in the mutant.
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Specimen
S8E:
(close )
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Genetic Background:
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involves: C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Nes-cre)1Kln/0
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Age:
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postnatal day 60
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S8G:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Itgb8tm2Lfr/Itgb8tm2Lfr
Tg(Nes-cre)1Kln/0
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Age:
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postnatal day 60
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
astrocyte of the cerebral cortex |
Present |
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S8G
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Increased numbers of astrocytes were noted in the mutant.
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Analysis Tools
