Gene Expression Data
Assay Details
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Assay
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Reference:
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J:297073
Chen Z, et al., The vascular endothelial cell-expressed prion protein doppel promotes angiogenesis and blood-brain barrier development. Development. 2020 Sep 23;147(18):dev193094
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7281339
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Gene symbol:
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Prnd
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Gene name:
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prion like protein doppel
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Results
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Specimen
1E E14.5:
embryonic day 14.5
(more  )
Specimen
1E E14.5:
(close  )
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Genetic Background:
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involves: FVB/N
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: brain blood vessel |
blood vessel endothelial cell |
Present |
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1E E14.5
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Expression in blood vessels of brain as early as E14.5.
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Specimen
1E E17.5:
embryonic day 17.5
(more )
Specimen
1E E17.5:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS25: brain blood vessel |
blood vessel endothelial cell |
Present |
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1E E17.5
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Expression persisted in later embryonic stages.
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Specimen
1E P7:
postnatal day 7
(more )
Specimen
1E P7:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
1E P21:
postnatal day 21
(more )
Specimen
1E P21:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: brain blood vessel |
blood vessel endothelial cell |
Ambiguous |
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1E P21
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Authors diminished in most blood vessels at P21.
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Specimen
S2C:
postnatal adult
(more )
Specimen
S2C:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: cerebellum |
blood vessel endothelial cell |
Present |
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S2C
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Specimen
S2D:
(close )
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Genetic Background:
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involves: FVB/N
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Mutant Allele(s):
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Prndtm1Sbp/Prndtm1Sbp
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S2E:
postnatal adult
(more )
Specimen
S2E:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S2F:
(close )
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Genetic Background:
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involves: FVB/N
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Mutant Allele(s):
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Prndtm1Sbp/Prndtm1Sbp
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S2G:
postnatal adult
(more )
Specimen
S2G:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: intestine |
blood vessel endothelial cell |
Present |
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S2G
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Expression in intestinal microvilli.
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Specimen
S2H:
(close )
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Genetic Background:
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involves: FVB/N
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Mutant Allele(s):
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Prndtm1Sbp/Prndtm1Sbp
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S2I:
postnatal adult
(more )
Specimen
S2I:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal adult
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Sex:
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Male
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S2J:
(close )
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Genetic Background:
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involves: FVB/N
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Mutant Allele(s):
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Prndtm1Sbp/Prndtm1Sbp
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Age:
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postnatal adult
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Sex:
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Male
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
S9B:
postnatal day 7
(more )
Specimen
S9B:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina blood vessel |
retinal blood vessel endothelial cell |
Present |
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S9B
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Expression in sprouting blood vessels of primary vascular plexus.
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Specimen
S9C:
postnatal day 14
(more )
Specimen
S9C:
(close )
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Genetic Background:
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involves: FVB/N
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Age:
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postnatal day 14
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina blood vessel |
retinal blood vessel endothelial cell |
Present |
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S9C
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Expression in secondary vascular plexi.
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