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Gene Expression Data
Assay Details
Assay
Reference: J:317089 Du J, et al., FHL2 mediates tooth development and human dental pulp cell differentiation into odontoblasts, partially by interacting with Runx2. J Mol Histol. 2016 Apr;47(2):195-202
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258371
Gene symbol: Fhl2
Gene name: four and a half LIM domains 2
Antibody: anti-FHL2
Results
Specimen 1B: embryonic day 13.5 (more )
Note: Bud stage of tooth development. Double labeled: red - Fhl2; green - Runx2 (assay MGI:7258372).
Structure Level Pattern Image Note
TS21: enamel organ Present 1F , 1B , 1E
TS21: molar mesenchyme Present Regionally restricted 1E , 1B Expression is in the mesenchyme underlying the enamel organ and is primarily localized in the cytosol.
Specimen 2B: embryonic day 14.5 (more )
Note: Cap stage of tooth development. Double labeled: red - Fhl2; green - Runx2 (assay MGI:7258372).
Structure Level Pattern Image Note
TS22: dental sac Present 2F , 2B , 2E Expression is primarily in the cytosol.
TS22: enamel knot Present 2F , 2B , 2E Expression is primarily in the cytosol.
TS22: inner enamel epithelium Present 2F , 2B , 2E Expression is primarily in the cytosol.
TS22: molar dental papilla Present 2F , 2B , 2E Expression is primarily in the cytosol.
TS22: outer enamel epithelium Present 2F , 2B , 2E Expression is primarily in the cytosol.
TS22: stellate reticulum Present 2F , 2B , 2E Expression is primarily in the cytosol.
Specimen 3B: embryonic day 16.5 (more )
Note: Early bell stage of tooth development. Double labeled: red - Fhl2; green - Runx2 (assay MGI:7258372).
Structure Level Pattern Image Note
TS24: inner enamel epithelium Present 3B , 3F , 3E Expression is primarily in the cytosol.
TS24: molar dental papilla Present 3B , 3F , 3E Expression is primarily in the cytosol.
TS24: outer enamel epithelium Present 3B , 3F , 3E Expression is primarily in the cytosol.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory