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Cplane2em1Kvand
Endonuclease-mediated Allele Detail
Summary
Symbol: Cplane2em1Kvand
Name: ciliogenesis and planar polarity effector 2; endonuclease-mediated mutation 1, Kathryn Anderson
MGI ID: MGI:6887372
Synonyms: Rsg1CRISPR
Gene: Cplane2  Location: Chr4:140941249-140947425 bp, + strand  Genetic Position: Chr4, 73.47 cM
Alliance: Cplane2em1Kvand page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Not Applicable)
Mutation:    Insertion
 
Mutation detailsCRISPR/Cas9 technology generated a 2-bp insertion immediately downstream of codon 69, leading to a frame shift and deletion of essential motifs of the GTPase domain. (J:255486)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cplane2 Mutation:  19 strains or lines available
References
Original:  J:255486 Agbu SO, et al., The small GTPase RSG1 controls a final step in primary cilia initiation. J Cell Biol. 2018 Jan 2;217(1):413-427
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory