Gene Expression Data
Assay Details
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Assay
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Reference:
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J:317359
Sakamachi Y, et al., TAK1 regulates resident macrophages by protecting lysosomal integrity. Cell Death Dis. 2017 Feb 9;8(2):e2598
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6883603
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Gene symbol:
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Adgre1
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Gene name:
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adhesion G protein-coupled receptor E1
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Antibody:
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Anti F4/80 (BM8)
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Detection system:
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Secondary antibody coupled to Alexa Fluor 594
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Results
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Specimen
3c Control:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Map3k7tm1.1Aki/Map3k7tm1.1Aki
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3c Tak1 HKO:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * CBA/Ca
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Mutant Allele(s):
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Commd10Tg(Vav1-icre)A2Kio/0
Map3k7tm1.1Aki/Map3k7tm1.1Aki
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: thymus |
thymic macrophage |
Weak |
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3c Tak1 HKO
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Expression markedly reduced compared with controls
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Specimen
3f Control:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Map3k7tm1.1Aki/Map3k7tm1.1Aki
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3f Tak1 HKO:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * CBA/Ca
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Mutant Allele(s):
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Commd10Tg(Vav1-icre)A2Kio/0
Map3k7tm1.1Aki/Map3k7tm1.1Aki
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: lung |
lung macrophage |
Weak |
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3f Tak1 HKO
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Expression markedly reduced compared with controls
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Specimen
Spleen Control not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Map3k7tm1.1Aki/Map3k7tm1.1Aki
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: spleen |
splenic macrophage |
Present |
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Specimen
Spleen Tak1 HKO not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * CBA/Ca
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Mutant Allele(s):
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Commd10Tg(Vav1-icre)A2Kio/0
Map3k7tm1.1Aki/Map3k7tm1.1Aki
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS27: spleen |
splenic macrophage |
Weak |
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Expression markedly reduced compared with controls
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)
Analysis Tools