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Gene Expression Data
Assay Details
Assay
Reference: J:123297 Gazdag E, et al., Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development. Reproduction. 2007 Jul;134(1):51-62
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6864063
Gene symbol: Tbpl2
Gene name: TATA box binding protein like 2
Antibody: anti-TBP2 2B12
Detection system: Secondary antibody
Results
Specimen 2Ac: postnatal week 12 (more )
Note: Primordial follicle. Double labeled: red - Tbpl2; green - Tbp (assay MGI:6864054).
Structure Level Pattern Image Note
TS28: oocyte of primordial follicle Present 2Ac , 2Ad Expression is in the nuclei and is excluded from the nucleoli and localizes to regions of noncondensed chromatin in oocytes with a non-surrounded nucleolus.

Specimen 2Ag: postnatal week 12 (more )
Note: Primary follicle. Double labeled: red - Tbpl2; green - Tbp (assay MGI:6864054).
Structure Level Pattern Image Note
TS28: oocyte of primary follicle Present 2Ag , 2Ah Expression is excluded from the nucleoli and localizes to regions of noncondensed chromatin in oocytes with a non-surrounded nucleolus.
TS28: follicle cell of primary follicle Absent 2Ah , 2Ag

Specimen 2Ak: postnatal week 12 (more )
Note: Preantral secondary follicle. Double labeled: red - Tbpl2; green - Tbp (assay MGI:6864054).
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Present 2Ak , 2Al Expression is excluded from the nucleoli and localizes to regions of noncondensed chromatin in oocytes with a partly non-surrounded nucleolus.
TS28: ovary preantral follicle Absent 2Ak , 2Al

Specimen 2Ao: postnatal week 12 (more )
Note: Antral secondary follicle. Double labeled: red - Tbpl2; green - Tbp (assay MGI:6864054).
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Present 2Ao , 2Ap Expression is excluded from the nucleoli and localizes to regions of noncondensed chromatin in oocytes with a partly non-surrounded nucleolus.
TS28: follicle cell of antral follicle Absent 2Ao , 2Ap

Specimen 2As: postnatal week 12 (more )
Note: Preovulatory follicle. Double labeled: red - Tbpl2; green - Tbp (assay MGI:6864054).
Structure Level Pattern Image Note
TS28: ovary follicle cell Absent 2At , 2As
TS28: secondary oocyte Absent 2At , 2As

Specimen 2Bc: postnatal week 4 (more )
Note: Double labeled: green - Tbpl2; red - Ddx4 (assay MGI:6864053).
Structure Level Pattern Image Note
TS28: primary oocyte Absent 2Bc , 2Bd

Specimen 3p: embryonic day 0.5 (more )
Note: Zygote.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Absent 3p

Specimen 3t: embryonic day 1.0 (more )
Note: 2-cell stage embryo.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Absent 3t

Specimen 4Aa: postnatal week 10 (more )
Note: Primodial follicle.
Structure Level Pattern Image Note
TS28: oocyte of primordial follicle Present 4Aa

Specimen 4Ab: postnatal week 10; Gdf9tm1Zuk/Gdf9tm1Zuk (more )
Note: Primodial follicle.
Structure Level Pattern Image Note
TS28: oocyte of primordial follicle Present 4Ab

Specimen 4Ac: postnatal week 6; Npm2tm1Zuk/Npm2tm1Zuk (more )
Note: Primodial follicle.
Structure Level Pattern Image Note
TS28: oocyte of primordial follicle Present 4Ac Expression in this mutant is similar to wild-type.

Specimen 4Ad: postnatal week 10; Noboxtm1Rajk/Noboxtm1Rajk (more )
Note: Primodial follicle.
Structure Level Pattern Image Note
TS28: oocyte of primordial follicle Present 4Ad Oocytes in this mutant have expression, but the protein is abnormally diffused into the ooplasm.

Specimen 4Ae: postnatal week 10 (more )
Note: Primary follicle.
Structure Level Pattern Image Note
TS28: oocyte of primary follicle Present 4Ae

Specimen 4Af: postnatal week 10; Gdf9tm1Zuk/Gdf9tm1Zuk (more )
Note: Primary follicle.
Structure Level Pattern Image Note
TS28: oocyte of primary follicle Absent 4Af

Specimen 4Ag: postnatal week 6; Npm2tm1Zuk/Npm2tm1Zuk (more )
Note: Primary follicle.
Structure Level Pattern Image Note
TS28: oocyte of primary follicle Present 4Ag Expression in this mutant is similar to wild-type.

Specimen 4Ah: postnatal week 10 (more )
Note: Secondary follicle.
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Present 4Ah

Specimen 4Ai: postnatal week 10; Gdf9tm1Zuk/Gdf9tm1Zuk (more )
Note: Secondary follicle.
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Absent 4Ai

Specimen 4Aj: postnatal week 6; Npm2tm1Zuk/Npm2tm1Zuk (more )
Note: Secondary follicle.
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Present 4Aj Expression in this mutant is similar to wild-type.

Specimen 4Ak: postnatal week 10 (more )
Note: Antral secondary follicle.
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Present 4Ak

Specimen 4Al: postnatal week 6; Npm2tm1Zuk/Npm2tm1Zuk (more )
Note: Antral secondary follicle.
Structure Level Pattern Image Note
TS28: oocyte of secondary follicle Present 4Al Expression in this mutant is similar to wild-type.

Specimen 4Am: postnatal week 10 (more )
Note: Antral preovulatory follicle.
Structure Level Pattern Image Note
TS28: secondary oocyte Absent 4Am

Specimen 4An: postnatal week 6; Npm2tm1Zuk/Npm2tm1Zuk (more )
Note: Antral preovulatory follicle.
Structure Level Pattern Image Note
TS28: secondary oocyte Strong 4An Expression is associated to the non-condensed chromatin.

Specimen 4Ba: postnatal day 1 (more )
Note: Early primary oocyte.
Structure Level Pattern Image Note
TS27: primary oocyte Absent 4Ba

Specimen 4Bb: postnatal day 1; Noboxtm1Rajk/Noboxtm1Rajk (more )
Note: Early primary oocyte.
Structure Level Pattern Image Note
TS27: primary oocyte Strong 4Bb Expression is nuclear.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory