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Gene Expression Data
Assay Details
Assay
Reference: J:314578 Mi Y, et al., A Novel Function of TET2 in CNS: Sustaining Neuronal Survival. Int J Mol Sci. 2015 Sep 10;16(9):21846-57
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6860437
Gene symbol: Tet2
Gene name: tet methylcytosine dioxygenase 2
Antibody: TET2 antibody (21207-1-AP)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A (left): postnatal week 8 (more )
Note: Double labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 2A TET2/NeuN (left) Expression in most neurons and a few other cells - possibly oligodendrocytes and astrocytes.
Specimen 2A (right): postnatal week 8 (more )
Note: Triple labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438); blue - DAPI.
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 2A TET2 , 2A TET2/DAPI , 2A TET2/NeuN (right) Expression mainly in cytoplasm and less in nucleus.
Specimen 2B CA1 (left): postnatal week 8 (more )
Note: Double labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 2B CA1 TET2/NeuN (left) Similar pattern of expression as seen in upper cortex.
Specimen 2B CA1 (right): postnatal week 8 (more )
Note: Triple labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438); blue - DAPI.
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present Regionally restricted 2B CA1 TET2/NeuN (right) , 2B CA1 TET2/DAPI , 2B CA1 TET2 Expression mainly in cytoplasm and less in nucleus.
Specimen 2B CA3 (left): postnatal week 8 (more )
Note: Double labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438).
Structure Level Pattern Image Note
TS28: hippocampus CA2 Present Regionally restricted 2B CA3 TET2/NeuN (left) Similar pattern of expression as seen in upper cortex.
Specimen 2B CA3 (right): postnatal week 8 (more )
Note: Triple labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438); blue - DAPI.
Structure Level Pattern Image Note
TS28: hippocampus CA2 Present Regionally restricted 2B CA3 TET2/NeuN (right) , 2B CA3 TET2/DAPI , 2B CA3 TET2 Expression mainly in cytoplasm and less in nucleus.
Specimen 2B DG (left): postnatal week 8 (more )
Note: Double labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438).
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 2B DG TET2/NeuN (left) Similar pattern of expression as seen in upper cortex.
Specimen 2B DG (right): postnatal week 8 (more )
Note: Triple labeled: green - Tet2; red - NeuN (Rbfox3 assay MGI:6860438); blue - DAPI.
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 2B DG TET2 , 2B DG TET2/NeuN (right) , 2B DG TET2/DAPI Expression mainly in cytoplasm and less in nucleus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory