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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: RT-PCR
MGI Accession ID: MGI:6831089
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Probe: Lef1-pW, Lef1-pX
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to beta-actin or Gapdh.
Results
Image: 4H Lef1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
Prrx1Cre;Stat3C/+ P0 TS27: humerus Present 1.5 µg; total RNA involves: C57BL/6 * SJL/J Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0Not Specified Conditional mutant. Bone marrow and cartilage were removed.
Prrx1Cre;Stat3C/C P0 TS27: humerus Present (a) 1.5 µg; total RNA involves: C57BL/6 * SJL/J Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0Not Specified Conditional mutant. Bone marrow and cartilage were removed.
Notes:
(a) There was a significant reduction in expression in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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