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Gene Expression Data
Assay Details
Assay
Reference: J:98098 Sum EY, et al., The LIM domain protein Lmo4 is highly expressed in proliferating mouse epithelial tissues. J Histochem Cytochem. 2005 Apr;53(4):475-86
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6827302
Gene symbol: Lmo4
Gene name: LIM domain only 4
Reporter: lacZ
Direct Detection
Assay notes: Specimens were fixed in 2% paraformaldehyde and 0.25% glutaraldehyde and postfixed in 4% paraformaldehyde.
Results
Specimen 3A: postnatal week 18; Lmo4tm3Sho/Lmo4+ (more )
Structure Level Pattern Image Note
TS28: thymus cortex Strong Regionally restricted 3A Expression is in cortical thymocytes.

Specimen 3D: postnatal week 18; Lmo4tm3Sho/Lmo4+ (more )
Structure Level Pattern Image Note
TS28: alveolus epithelium Present Regionally restricted 3D Expression is in the low columnar epithelial cells.
TS28: bronchiole epithelium Present Regionally restricted 3D Expression is in the low columnar epithelial cells.
TS28: respiratory bronchiole epithelium Present Regionally restricted 3D Expression is in the low columnar epithelial cells.

Specimen 3G: postnatal week 18; Lmo4tm3Sho/Lmo4+ (more )
Structure Level Pattern Image Note
TS28: islets of Langerhans Very strong 3G
TS28: pancreatic duct Weak Regionally restricted 3G Expression is in epithelial cells lining the pancreatic ducts.
TS28: pancreatic acinus Absent 3G

Specimen 3J: postnatal week 18; Lmo4tm3Sho/Lmo4+ (more )
Structure Level Pattern Image Note
TS28: juxtaglomerular complex Strong 3J
TS28: distal convoluted tubule Present 3J
TS28: renal proximal convoluted tubule Present 3J
TS28: renal tubule Present 3J
TS28: metanephros Weak 3J The majority of cells in the kidney had low expression.
TS28: glomerular tuft Absent 3J

Specimen 4A: postnatal week 12; Lmo4tm3Sho/Lmo4+ (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 4A
TS28: sebaceous gland Present 4A
TS28: hair bulb Present Regionally restricted 4A Expression is in undifferentiated bulb cells.
TS28: epidermis basal layer Present Regionally restricted 4A Expression is in squamous epithelial cells.

Specimen 4D: postnatal week 12; Lmo4tm3Sho/Lmo4+ (more )
Structure Level Pattern Image Note
TS28: tongue epithelium Present Regionally restricted 4D Expression is in the stratified squamous epithelial cells of the tongue, with the majority of expression confined to the basal layer of the germinativum.

Specimen 4G: postnatal week 12; Lmo4tm3Sho/Lmo4+ (more )
Structure Level Pattern Image Note
TS28: endometrium epithelium Strong 4G Expression is cytoplasmic.
TS28: myometrium Present 4G

Specimen 4J: postnatal week 12; Lmo4tm3Sho/Lmo4+ (more )
Note: The mid-pregnant mammary gland.
Structure Level Pattern Image Note
TS28: mammary gland Present 4J Expression is in both the ductal and lobuloalveolar epithelial cells with lower levels in the myoepithelium and surrounding stroma.
TS28: mammary gland luminal epithelium Present 4J
TS28: mammary gland duct Present Regionally restricted 4J Expression is in epithelial cells.
TS28: mammary gland myoepithelium Weak 4J


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory