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Gene Expression Data
Assay Details
Assay
Reference: J:312349 van Ineveld RL, et al., LGR6 marks nephron progenitor cells. Dev Dyn. 2021 Nov;250(11):1568-1583
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6818667
Gene symbol: Lgr6
Gene name: leucine-rich repeat-containing G protein-coupled receptor 6
Reporter: GFP
Antibody: anti-GFP (Abcam)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B: embryonic day 11.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: green - Lgr6 reporter; magenta - Six2 (assay MGI:6822332); blue - Cdh1 (assay MGI:6822333).
Structure Level Pattern Image Note
TS19: cap mesenchyme Present Single cells 1B green , 1B merge
Specimen 1C: embryonic day 12.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: green - Lgr6 reporter; magenta - Six2 (assay MGI:6822332); blue - Cdh1 (assay MGI:6822333).
Structure Level Pattern Image Note
TS20: cap mesenchyme Present 1C merge , 1C green
TS20: pretubular aggregate Present 1C merge , 1C green
Specimen 1D: embryonic day 13.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: green - Lgr6 reporter; magenta - Six2 (assay MGI:6822332); blue - Cdh1 (assay MGI:6822333).
Structure Level Pattern Image Note
TS21: cap mesenchyme Present 1D
TS21: pretubular aggregate Present 1D
TS21: renal vesicle Present 1D
TS21: s-shaped body Present 1D
Specimen 1E: embryonic day 13.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: green - Lgr6 reporter; magenta - Six2 (assay MGI:6822332); blue - Cdh1 (assay MGI:6822333).
Structure Level Pattern Image Note
TS21: renal vesicle Present 1E green , 1E merge
TS21: s-shaped body Present 1E green , 1E merge
Specimen 5A - left: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: green - Lgr6 reporter; magenta - Six2 (assay MGI:6822332); blue - Cdh1 (assay MGI:6822333).
Structure Level Pattern Image Note
TS27: cap mesenchyme Present 5A left
Specimen 5A - center: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: green - Lgr6 reporter; magenta - Six2 (assay MGI:6822332); blue - Cdh1 (assay MGI:6822333).
Structure Level Pattern Image Note
TS27: pretubular aggregate Present 5A center
Specimen 5A - right: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: green - Lgr6 reporter; magenta - Six2 (assay MGI:6822332); blue - Cdh1 (assay MGI:6822333).
Structure Level Pattern Image Note
TS27: renal vesicle Present 5A right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory