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Gene Expression Data
Assay Details
Assay
Reference: J:309563 Rafipay A, et al., Knockdown of slit signaling during limb development leads to a reduction in humerus length. Dev Dyn. 2021 Sep;250(9):1340-1357
Assay type: RNA in situ
MGI Accession ID: MGI:6780202
Gene symbol: Slit3
Gene name: slit guidance ligand 3
Probe: mSlit3 probe4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 1C Expression in proximal limb mesenchyme.
Specimen 1C': embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindlimb mesenchyme Present Regionally restricted 1C' Expression in proximal limb mesenchyme.
Specimen 1I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb interdigital region mesenchyme Strong Regionally restricted 1I Expression intensified from E13.5 to E15.5. Expression along proximal digit borders, with broader regions of expression just proximal to presumptive joint regions.
Specimen 1I': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindlimb interdigital region mesenchyme Strong Regionally restricted 1I' Expression intensified from E13.5 to E15.5. Expression along proximal digit borders, with broader regions of expression just proximal to presumptive joint regions.
Specimen 1O: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb interdigital region mesenchyme Strong Regionally restricted 1O Expression intensified from E13.5 to E15.5. Expression along proximal digit borders, with broader regions of expression just proximal to presumptive joint regions.
TS23: forelimb distal interphalangeal joint Weak 1O
Specimen 1O': embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hindlimb interdigital region mesenchyme Strong Regionally restricted 1O' Expression intensified from E13.5 to E15.5. Expression along proximal digit borders, with broader regions of expression just proximal to presumptive joint regions.
TS23: hindlimb distal interphalangeal joint Weak 1O'
Specimen 1U: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb interdigital region mesenchyme Strong Regionally restricted 1U Strong expression surrounding digits.
TS23: hand mesenchyme Strong Regionally restricted 1U Strong expression in mesenchyme ventral to digits.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory