About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:81151 Rodrigo I, et al., Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome. Development. 2003 Feb;130(3):473-82
Assay type: RNA in situ
MGI Accession ID: MGI:6771303
Gene symbol: Nkx3-2
Gene name: NK3 homeobox 2
Probe: Bapx1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present 1G
TS19: mesenchyme derived from splanchnopleure Present 1G
TS19: sclerotome Present 1G
TS19: 1st branchial arch Present Regionally restricted 1G Expression is in the mandibular region.

Specimen 1H: embryonic day 11.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present 1H Expression in this tissue is the same as in wild-type embryos.
TS19: limb mesenchyme Present 1H Expression in this tissue is the same as in wild-type embryos.
TS19: mesenchyme derived from splanchnopleure Present 1H Expression in this tissue is the same as in wild-type embryos.
TS19: sclerotome Absent 1H

Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sclerotome Present 2A

Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sclerotome Present 2B

Specimen 2C: embryonic day 11.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS19: sclerotome Absent 2C

Specimen 2D: embryonic day 11.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS19: sclerotome Absent 2D

Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: sclerotome Present 3A

Specimen 3B: embryonic day 9.5; Pax1tm1Neu/Pax1tm1Neu (more )
Structure Level Pattern Image Note
TS15: sclerotome Weak 3B

Specimen 3C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: sclerotome Present 3C

Specimen 3D: embryonic day 9.5; Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS15: sclerotome Present 3D Expression in this mutantis the same as in wild-type embryos.

Specimen 3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sclerotome Present 3E

Specimen 3F: embryonic day 10.5; Pax1tm1Neu/Pax1tm1Neu (more )
Structure Level Pattern Image Note
TS17: sclerotome Weak 3F

Specimen 3G: embryonic day 10.5; Pax1tm1Neu/Pax1+, Pax9tm1Rbal/Pax9tm1Rbal (more )
Structure Level Pattern Image Note
TS17: sclerotome Weak 3G

Specimen 3H: embryonic day 10.5; Pax1tm1Neu/Pax1tm1Neu, Pax9tm1Rbal/Pax9+ (more )
Structure Level Pattern Image Note
TS17: sclerotome Trace 3H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory