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Gene Expression Data
Assay Details
Assay
Reference: J:297051 Wang S, et al., RYK-mediated filopodial pathfinding facilitates midgut elongation. Development. 2020 Oct 27;147(20):dev195388
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6761382
Gene symbol: Ror2
Gene name: receptor tyrosine kinase-like orphan receptor 2
Antibody: anti-ROR2 (AB_10804796)
Detection system: Secondary antibody
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midgut epithelium Strong 1A
TS17: midgut mesenchyme Present 1A
Specimen 1B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midgut epithelium Strong 1B
TS19: midgut mesenchyme Present 1B
Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midgut epithelium Very strong 1C
TS20: midgut mesenchyme Present 1C
Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: midgut epithelium Weak 1D
TS21: midgut mesenchyme Weak 1D
Specimen 1E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midgut epithelium Weak 1E
TS22: midgut mesenchyme Weak 1E
Specimen 1F: embryonic day 14.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS22: midgut epithelium Present 1G' , 1F , 1G Expression is restricted to the basolateral membrane of all cells and is absent at the apical surface.
TS22: midgut mesenchyme Present Regionally restricted 1H' , 1F , 1H Expression is on the entire cell membrane of nearly all cells, with varying intensity.
Specimen 1P: embryonic day 14.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Ror2tm1.1Meg/Ror2tm1.1Meg (more )
Structure Level Pattern Image Note
TS22: midgut epithelium Present 1P , 1Q
TS22: midgut mesenchyme Present 1P , 1Q
Specimen 1R: embryonic day 14.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Ror2tm1.1Meg/Ror2tm1.1Meg, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: midgut mesenchyme Present 1R , 1S
TS22: midgut epithelium Absent 1S , 1R
Specimen 2E: embryonic day 14.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Ror2tm1.1Meg/Ror2tm1.1Meg (more )
Structure Level Pattern Image Note
TS22: midgut epithelium Present 2E , 2E'
TS22: midgut mesenchyme Present 2E , 2E'
Specimen 2F: embryonic day 14.5; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Ror2tm1.1Meg/Ror2tm1.1Meg, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: midgut epithelium Present 2F , 2F'
TS22: midgut mesenchyme Absent 2F , 2F'
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory