Gene Expression Data
Assay Details
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Assay
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Reference:
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J:94639
Diep DB, et al., Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain. Brain Res Dev Brain Res. 2004 Nov 25;153(2):261-70
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6761301
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Gene symbol:
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Dkk2
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Gene name:
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dickkopf WNT signaling pathway inhibitor 2
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Probe:
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Dkk2 probe4
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
1A:
embryonic day 12.0
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: head mesenchyme |
Present |
Regionally restricted |
1A
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Expression in mesenchyme surrounding rostral forebrain.
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Specimen
1B:
embryonic day 12.0
(more )
Specimen
1B:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: thalamus |
Present |
Regionally restricted |
1B
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Expression in circumscribed area in ventricular zone of dorsal thalamus.
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| TS20: head mesenchyme |
Present |
Regionally restricted |
1B
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Expression in mesenchyme surrounding rostral forebrain.
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Specimen
1B inset:
embryonic day 12.0
(more )
Specimen
1B inset:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: thalamus |
Present |
Regionally restricted |
1B inset
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Expression in anterior thalamic neuroepithelium.
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Specimen
1C:
embryonic day 12.0
(more )
Specimen
1C:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: forebrain |
Present |
Regionally restricted |
1C
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No expression in caudal region of forebrain.
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Specimen
P0 not shown:
postnatal day 0
(more )
Specimen
P0 not shown:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
4B:
embryonic day 12.5
(more )
Specimen
4B:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: eye mesenchyme |
Present |
Regionally restricted |
4B
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Expression in mesenchyme surrounding the eye that condenses into sclera and iris.
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Specimen
4E:
embryonic day 15.5
(more )
Specimen
4E:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: eye mesenchyme |
Present |
Regionally restricted |
4E
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Expression in mesenchyme surrounding the eye that condenses into sclera and iris.
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Specimen
6E W: dkk2:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
6E W: dkk2:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
6E W: dkk2 inset
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6E W: dkk2
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| TS21: cortical hem |
Absent |
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6E W: dkk2 inset
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6E W: dkk2
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Specimen
6E M: dkk2:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
6E M: dkk2
,
6E M: dkk2 inset
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No significant difference in expression between wild-type and mutant in hippocampal and thalamic structures.
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| TS21: cortical hem |
Absent |
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6E M: dkk2 inset
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6E M: dkk2
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Analysis Tools