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Gene Expression Data
Assay Details
Assay
Reference: J:288632 McGinty JW, et al., Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. Immunity. 2020 Mar 17;52(3):528-541.e7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6757200
Gene symbol: Alox5
Gene name: arachidonate 5-lipoxygenase
Antibody: anti-5-LO (SAB1410449)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5C: postnatal week 6-12 (more )
Note: Uninfected animal. Double labeled: gray - Alox5; red - Dclk1 (assay MGI:6757199).
Structure Level Pattern Image Note
TS28: duodenum epithelium Present Single cells 5C gray , 5C merge Expression is seen in tuft cells in the proximal small intestine.
Specimen 7H - proximal: postnatal week 6-12 (more )
Note: Uninfected animal. Double labeled: gray - Alox5; red - Dclk1 (assay MGI:6757199).
Structure Level Pattern Image Note
TS28: duodenum epithelium Present Single cells 7H upper Expression is seen in tuft cells in the proximal small intestine.
Specimen 7H - distal: postnatal week 6-12 (more )
Note: Uninfected animal. Double labeled: gray - Alox5; red - Dclk1 (assay MGI:6757199).
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Single cells 7H lower Expression is seen in tuft cells in the distal small intestine.
Specimen S5B: postnatal week 6-12 (more )
Note: Uninfected animal. Double labeled: gray - Alox5; red - Dclk1 (assay MGI:6757199).
Structure Level Pattern Image Note
TS28: duodenum epithelium Present Single cells S5B left Expression is seen in tuft cells in the proximal small intestine.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory