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Gene Expression Data
Assay Details
Assay
Reference: J:241394 Mattiske T, et al., Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene. Hum Mol Genet. 2016 Dec 15;25(24):5433-5443
Assay type: RT-PCR
MGI Accession ID: MGI:6753132
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Probe: Mm03003557_s1
Probe preparation: labelled with FAM
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Tbp. Data are summarized in Table S3A.
Results Image: S3B Six2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
WT E12.5 TS20: telencephalon Present 1 µg; total RNA Not Specified Not Specified
PA1 E12.5 TS20: telencephalon Present (a) 1 µg; total RNA involves: 129S/SvEv * C57BL/6 Arxtm4Kki/Arxtm4KkiNot Specified
PA2 E12.5 TS20: telencephalon Present (b) 1 µg; total RNA involves: 129S/SvEv * C57BL/6 Arxtm5Kki/Arxtm5KkiNot Specified
WT E14.5 TS22: telencephalon Present 1 µg; total RNA Not Specified Not Specified
PA1 E14.5 TS22: telencephalon Present (c) 1 µg; total RNA involves: 129S/SvEv * C57BL/6 Arxtm4Kki/Arxtm4KkiNot Specified
PA2 E14.5 TS22: telencephalon Present (d) 1 µg; total RNA involves: 129S/SvEv * C57BL/6 Arxtm5Kki/Arxtm5KkiNot Specified
WT E18.5 TS26: telencephalon Present 1 µg; total RNA Not Specified Not Specified
PA1 E18.5 TS26: telencephalon Present (e) 1 µg; total RNA involves: 129S/SvEv * C57BL/6 Arxtm4Kki/Arxtm4KkiNot Specified
PA2 E18.5 TS26: telencephalon Present (f) 1 µg; total RNA involves: 129S/SvEv * C57BL/6 Arxtm5Kki/Arxtm5KkiNot Specified
Notes:
(a) Expression was downregulated, -35.05% relative to wild-type.
(b) Expression was downregulated, -21.14% relative to wild-type.
(c) Expression was downregulated, -31.96% relative to wild-type.
(d) Expression was downregulated, -35.49% relative to wild-type.
(e) Expression was downregulated, -4.63% relative to wild-type.
(f) Expression was upregulated, 10.69% relative to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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