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Gene Expression Data
Assay Details
Assay
Reference: J:306155 Goodyer WR, et al., Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. Circ Res. 2019 Aug 2;125(4):379-397
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6730345
Gene symbol: Rgs6
Gene name: regulator of G-protein signaling 6
Antibody: Anti-RGS6 antibody (ab155809)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 8C-0: embryonic day 16.5 (more )
Note: Double labeled: green - Rgs6; red - Hcn4 (assay MGI:6730295).
Structure Level Pattern Image Note
TS24: sinoatrial node Present 8C4 , 8C7 Coexpressed with Hcn4.
TS24: impulse conducting system Present Regionally restricted 8C4 , 8C7 Expressed in transitional sinoatrial conduction pathways (Hcn4-/Rgs6+, or Hcn4+/Rgs6+).

Specimen 8C-90: embryonic day 16.5 (more )
Note: Double labeled: green - Rgs6; red - Hcn4 (assay MGI:6730295).
Structure Level Pattern Image Note
TS24: sinoatrial node Present 8C5 , 8C8 Coexpressed with Hcn4.
TS24: impulse conducting system Present Regionally restricted 8C5 , 8C8 Expressed in transitional sinoatrial conduction pathways (Hcn4-/Rgs6+, or Hcn4+/Rgs6+).

Specimen 8C-225: embryonic day 16.5 (more )
Note: Double labeled: green - Rgs6; red - Hcn4 (assay MGI:6730295).
Structure Level Pattern Image Note
TS24: impulse conducting system Present Regionally restricted 8C6 , 8C9 Expressed in transitional sinoatrial conduction pathways (Hcn4-/Rgs6+, or Hcn4+/Rgs6+).
TS24: sinoatrial node Present 8C9 , 8C6 Coexpressed with Hcn4.

Specimen S8B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: atrioventricular bundle Present S8B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory