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Gene Expression Data
Assay Details
Assay
Reference: J:253477 Bailey AS, et al., The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 2017 Oct 31;6:e26116
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6724552
Gene symbol: Dmc1
Gene name: DNA meiotic recombinase 1
Antibody: anti-Dmc1 (H-100; sc-22768)
Detection system: Alexa Fluor
Results
Specimen 4G: postnatal day 12 (more )
Note: Double labeled: red - Dmc1; blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Strong 4G

Specimen 4H: postnatal day 12; Ythdc2tm1b(EUCOMM)Hmgu/Ythdc2tm1b(EUCOMM)Hmgu (more )
Note: Double labeled: red - Dmc1; blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present Regionally restricted 4H High levels of expression only in a small percentage of tubules.

Specimen 4-S1C: postnatal day 12 (more )
Note: Double labeled: red - Dmc1; green - Ddx4 (assay MGI:6724548).
Structure Level Pattern Image Note
TS28: spermatocyte Strong 4 S1C

Specimen 4-S1D: postnatal day 12; Ythdc2tm1b(EUCOMM)Hmgu/Ythdc2tm1b(EUCOMM)Hmgu (more )
Note: Double labeled: red - Dmc1; green - Ddx4 (assay MGI:6724548).
Structure Level Pattern Image Note
TS28: seminiferous tubule Present Regionally restricted 4 S1D High levels of expression only in a small percentage of tubules.

Specimen 5M: embryonic day 15.5 (more )
Note: Double labeled: red - Dmc1; green - Ddx4 (assay MGI:6724548).
Structure Level Pattern Image Note
TS23: germ cell of ovary Strong 5M Abundant expression in germ cells.

Specimen 5N: embryonic day 15.5; Ythdc2tm1b(EUCOMM)Hmgu/Ythdc2tm1b(EUCOMM)Hmgu (more )
Note: Double labeled: red - Dmc1; green - Ddx4 (assay MGI:6724548).
Structure Level Pattern Image Note
TS23: germ cell of ovary Weak 5N Expression in few germ cells at E15.5.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory