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Gene Expression Data
Assay Details
Assay
Reference: J:253477 Bailey AS, et al., The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 2017 Oct 31;6:e26116
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6724542
Gene symbol: Ythdc2
Gene name: YTH domain containing 2
Antibody: YTHDC2 antibody (A303-026A)
Detection system: Alexa Fluor
Results
Specimen 1D: postnatal adult (more )
Note: Triple labeled: green - Ythdc2; red - Sycp3 (assay MGI:6724544); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present Regionally restricted 1D Expression in a subset of germ cells in a majority of seminiferous tubules.
Specimen 1E: postnatal adult (more )
Note: Triple labeled: green - Ythdc2; red - Sycp3 (assay MGI:6724544); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatogonium Absent 1E No expression in spermatogonia next to tubule wall.
TS28: spermatocyte Strong Regionally restricted 1E Strongly expressed in spermatocytes. Expression localized primarily to cytoplasm.
Specimen 1-S1A: postnatal day 10 (more )
Note: Triple labeled: green - Ythdc2 ; red - Ddx4 (assay MGI:6724548); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Absent 1 S1A , 1 S1A'
Specimen 1-S1B: postnatal day 12 (more )
Note: Triple labeled: green - Ythdc2 ; red - Ddx4 (assay MGI:6724548); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 1 S1B' , 1 S1B Expression increased between postnatal day 10 to day 12.
Specimen 1-S1C: postnatal day 14 (more )
Note: Triple labeled: green - Ythdc2 ; red - Ddx4 (assay MGI:6724548); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 1 S1C , 1 S1C'
Specimen 2-S1F: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 2 S1F
Specimen 2-S1G: postnatal day 14; Ythdc2tm1b(EUCOMM)Hmgu/Ythdc2tm1b(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Absent 2 S1G
Specimen 5-S1I: embryonic day 15.5 (more )
Note: Triple labeled: green - Ythdc2; red - Sycp3 (assay MGI:6724544); blue - DAPI.
Structure Level Pattern Image Note
TS23: germ cell of ovary Present 5 S1I
Specimen 9A: postnatal adult (more )
Note: Triple labeled: green - Ythdc2; red - Dcp1a (assay MGI:6724565); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 9A'' , 9A Expression in spermatocytes distributed throughout cytoplasm; also concentrated in perinuclear puncta.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory