About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:290712 Ishiguro KI, et al., MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. Dev Cell. 2020 Feb 24;52(4):429-445.e10
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6721112
Gene symbol: Sycp1
Gene name: synaptonemal complex protein 1
Antibody: Anti-Scp1 (Ab-15090)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4D WT: postnatal week 8 (more )
Note: Triple labeled: green - Sycp1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 4D WT Sycp1 , 4D WT (merge)
Specimen 4D Meiosin KO: postnatal day 8; Meiosinem1Keish/Meiosinem1Keish (more )
Note: Triple labeled: green - Sycp1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Ambiguous Regionally restricted 4D Meiosin KO (merge) , 4D Meiosin KO Sycp1 Expression not observed in Meiosin KO preleptotene-like cells.
Specimen 4D Sta8 KO: postnatal day 8; Stra8em4Keish/Stra8em4Keish (more )
Note: Triple labeled: green - Sycp1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 4D Stra8 KO (merge) , 4D Stra8 KO Sycp1
Specimen 7B E15.5 WT: embryonic day 15.5 (more )
Note: Triple labeled: green - Sycp1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS23: germ cell of ovary Present 7B E15.5 WT S1 , 7B E15.5 WT (merge)
Specimen 7B E15.5 Meiosin KO: embryonic day 15.5; Meiosinem1Keish/Meiosinem1Keish (more )
Note: Triple labeled: green - Sycp1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS23: germ cell of ovary Absent 7B E15.5 Meiosin KO (merge) , 7B E15.5 Meiosin KO S1
Specimen 7B E17.5 WT: embryonic day 17.5 (more )
Note: Triple labeled: green - Sycp1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS25: germ cell of ovary Present 7B E17.5 WT S1 , 7B E17.5 WT (merge)
Specimen 7B E17.5 Meiosin KO: embryonic day 17.5; Meiosinem1Keish/Meiosinem1Keish (more )
Note: Triple labeled: green - Sycp1; red - Sycp3 (assay MGI:6721101); blue - DAPI.
Structure Level Pattern Image Note
TS25: germ cell of ovary Absent 7B E17.5 Meiosin KO (merge) , 7B E17.5 Meiosin KO S1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory