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Gene Expression Data
Assay Details
Assay
Reference: J:241010 Mu W, et al., EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis. Dev Biol. 2017 Apr 15;424(2):198-207
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6721075
Gene symbol: H2ax
Gene name: H2A.X variant histone
Antibody: Anti-gamma H2AX
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4C Ctrl: postnatal month 1; Ezh1tm1Jnw/Ezh1+, Ezh2tm1Tara/Ezh2+, Tg(Ddx4-cre)1Dcas/0 (more )
Note: Conditional mutant. Double labeled: green - H2ax; red - Zbtb16 (assay MGI:6721115).
Structure Level Pattern Image Note
TS28: spermatocyte Present 4C Ctrl-3
Specimen 4C Mut: postnatal month 1; Ezh1tm1Jnw/Ezh1tm1Jnw, Ezh2tm1Tara/Ezh2tm1Tara, Tg(Ddx4-cre)1Dcas/0 (more )
Note: Conditional mutant. Double labeled: green - H2ax; red - Zbtb16 (assay MGI:6721115).
Structure Level Pattern Image Note
TS28: spermatocyte Present 4C DKO-3 Depletion of pachytene spermatocytes and spermatids.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory