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Gene Expression Data
Assay Details
Assay
Reference: J:231231 Abby E, et al., Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6716298
Gene symbol: Dmc1
Gene name: DNA meiotic recombinase 1
Results
Specimen S6b Lepto Meioc+/+: postnatal (more )
Note: Leptotene. Double labeled: green - Dmc1; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present S6b Lepto Meioc+/+ Dmc1 , S6b Lepto Meioc+/+ Dmc1/Sycp3
Specimen S6b Lepto Meioc-/-: postnatal; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Leptotene. Double labeled: green - Dmc1; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present S6b Lepto Meioc-/- Dmc1/Sycp3 , S6b Lepto Meioc-/- Dmc1 Dmc1-positive foci formed normally but persisted in mutants.
Specimen S6b Zygo Meioc+/+: postnatal (more )
Note: Zygotene. Double labeled: green - Dmc1; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present S6b Zygo Meioc+/+ Dmc1/Sycp3 , S6b Zygo Meioc+/+ Dmc1
Specimen S6b Zygo-like Meioc-/- top: postnatal; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Zygotene-like. Double labeled: green - Dmc1; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present S6b Zygo-Like Meioc-/- Dmc1 top , S6b Zygo-Like Meioc-/- Dmc1/Sycp3 top Dmc1-positive foci formed normally but persisted in mutants.
Specimen S6b Pachy Meioc+/+: postnatal (more )
Note: Pachytene. Double labeled: green - Dmc1; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present S6b Pachy Meioc+/+ Dmc1/Sycp3 , S6b Pachy Meioc+/+ Dmc1
Specimen S6b Zygo-like Meioc-/- bottom: postnatal; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Zygotene-like. Double labeled: green - Dmc1; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present S6b Zygo-Like Meioc-/- Dmc1 bottom , S6b Zygo-Like Meioc-/- Dmc1/Sycp3 bottom Dmc1-positive foci formed normally but persisted in mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory