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Gene Expression Data
Assay Details
Assay
Reference: J:184925 Wang Y, et al., PDGF mediates TGFbeta-induced migration during development of the spinous process. Dev Biol. 2012 May 1;365(1):110-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6715582
Gene symbol: Pdgfb
Gene name: platelet derived growth factor, B polypeptide
Antibody: anti-PDGF-BB
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Col2a1-cre)1Bhr/0, Tgfbr2tm1.2Hlm/Tgfbr2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: dorsal root ganglion Present 4A
TS23: lumbar vertebral cartilage condensation Present 4A
Specimen 4B: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Tg(Col2a1-cre)1Bhr/0, Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: lumbar vertebral cartilage condensation Weak 4B Expression reduced in cartilage.
TS23: dorsal root ganglion Weak 4B Expression comparable to that of control
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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