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Gene Expression Data
Assay Details
Assay
Reference: J:263030 Hu J, et al., WDR1-regulated actin dynamics is required for outflow tract and right ventricle development. Dev Biol. 2018 Jun 15;438(2):124-137
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6715555
Gene symbol: Tmod1
Gene name: tropomodulin 1
Results
Specimen 7G/I: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant. Double labeled: green - Tmod1; red - phalloidin.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Regionally restricted 7I , 7G Inner cellular layers were longitudinal striated cardiac myofibrils; expression aligned in striation. Outer monlolayer/bilayer complosed of closely condected cardioyocytes.

Specimen 7J/L: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant. Double labeled: green - Tmod1; red - phalloidin.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present Regionally restricted 7J , 7L Cardiomyocytes loosely and disorderly organized into multilayered myocardium. Number of striated longitudinal myofibrils decreased. Within F-actin accumulation, expression diffused by vigorous.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory