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Gene Expression Data
Assay Details
Assay
Reference: J:240991 Andrae J, et al., Characterization of platelet-derived growth factor-A expression in mouse tissues using a lacZ knock-in approach. PLoS One. 2014;9(8):e105477
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6715088
Gene symbol: Pdgfa
Gene name: platelet derived growth factor, alpha
Reporter: lacZ
Direct Detection
Results
Specimen 4a: embryonic day 9.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 4a right
TS15: otocyst Present 4a right
TS15: somite Present 4a right
TS15: tail Present 4a right
Specimen 4b: embryonic day 9.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 4b
TS15: otocyst Present 4b
TS15: somite Present 4b
TS15: tail Present 4b
Specimen 4c: embryonic day 9.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS15: somite Present 4c
Specimen 4d: embryonic day 9.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch endoderm Present 4d
TS15: otocyst epithelium Present 4d
Specimen 5a: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: back skin Present Regionally restricted 5a Expressed in developing hair follicles in the back skin.
TS22: forelimb muscle Present 5a
TS22: hindlimb muscle Present 5a
TS22: vibrissa Present 5a
TS22: thoracic segment of trunk Present Regionally restricted 5a Expressed in developing skeletal muscle in the thoracic region.
TS22: hair follicle Present Regionally restricted 5a Expressed in developing hair follicles in the back skin and eyebrows.
Specimen 5c: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: intestine Strong 5c left
Specimen 5d: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: lung epithelium Strong 5d left
TS22: lung mesenchyme Absent 5d left
Specimen 5e: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: heart Strong 5e left
Specimen 5f: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: dorsal aorta Strong 5f left
TS22: metanephros Strong 5f left
TS22: adrenal gland Weak 5f left
Specimen 5g: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: diaphragm Strong Regionally restricted 5g left Expressed in muscle fibers.
Specimen 5h: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: liver Weak Punctate 5h left
Specimen 6a: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: aorta Present 6a lower
Specimen 6b: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: blood vessel Present 6b right
TS25: brown fat Present 6b right
Specimen 6c: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: esophagus Present 6c lower
Specimen 6d: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: thymus Present 6d right
Specimen 6e: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: lung Present 6e right
Specimen 6f: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: heart Present 6f right
Specimen 6g: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: diaphragm Present 6g right
Specimen 6h: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: stomach Present 6h right
Specimen 6i: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: liver Present 6i right
Specimen 6j: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: spleen Present 6j right
Specimen 6k: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: intestine Present 6k right
Specimen 6l: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: metanephros Present 6l right
TS25: adrenal gland Weak 6l right
Specimen 6m: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: skin Present 6m right
Specimen 6n: embryonic day 17.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS25: brain Present 6n right
Specimen 7a: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: aorta Present 7a lower
Specimen 7b: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: blood vessel Present 7b right
TS28: brown fat Present 7b right
Specimen 7c: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: esophagus Present 7c lower
Specimen 7d: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: thymus Present 7d right
Specimen 7e: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: lung Present 7e right
Specimen 7f: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: heart Present 7f right
Specimen 7g: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 7g right
Specimen 7h: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: stomach Present 7h right
Specimen 7i: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: liver Present 7i right
Specimen 7j: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: spleen Present 7j right
Specimen 7k: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: pancreas Present 7k right
Specimen 7l: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: colon Present 7l right
Specimen 7m: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: metanephros Present 7m right
Specimen 7n: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: skin Present 7n right
Specimen 7o: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: brain Present 7o right
Specimen 7p: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: bladder Present 7p right
Specimen 7q: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: retina Present 7q right
Specimen 7r: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: rib Present 7r right
Specimen 8a: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: eyelid epithelium Present 8a
TS22: skin Present 8a
TS22: vibrissa Present 8a
TS22: hair follicle Present Regionally restricted 8a Expressed in eyebrow follicles.
Specimen 8b: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: cornea Present 8b
TS22: epidermis Present 8b
TS22: eyelid epithelium Present 8b
TS22: alimentary system smooth muscle Present Regionally restricted 8b Expressed in lacrimal gland.
TS22: hair follicle Present Regionally restricted 8b Expressed in eyebrow follicles.
Specimen 8c: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: epidermis Present 8c
TS22: facial muscle Present 8c
TS22: vibrissa Present 8c
Specimen 8d: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Present 8d
TS22: epidermis Present 8d
TS22: skeletal muscle Present 8d
TS22: surface ectoderm of genital tubercle Present 8d
TS22: vertebral cartilage condensation Present 8d
Specimen 8e: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: inner ear epithelium Present 8e
Specimen 8f: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: bronchus epithelium Present 8f
Specimen 8g: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: seminiferous cord Present 8g
TS22: male reproductive gland or organ Present Regionally restricted 8g Expressed in mesonephric ducts.
Specimen 8h: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: metanephros epithelium Present 8h
TS22: renal medulla Present 8h
TS22: dorsal aorta Present Regionally restricted 8h Expressed in vascular smooth muscle.
Specimen 8i: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: intestine epithelium Present 8i
TS22: intestine smooth muscle Present 8i
Specimen 8j: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: stomach epithelium Present 8j
TS22: stomach Present Regionally restricted 8j Expressed in developing muscle layers.
Specimen 8k: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: myocardium layer Present 8k
TS22: outflow tract cardiac muscle Strong 8k
TS22: dorsal aorta Present Regionally restricted 8k Expressed in vascular smooth muscle.
Specimen 8l: embryonic day 14.5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 8l Expressed in neuroepithelial tissue in the dorsal horn of the lateral ventricle.
TS22: amygdala Present 8l
TS22: hippocampus Present 8l
Specimen 9a: postnatal day 12; Pdgfatm1Vlcg/Pdgfa+ (more )
Note: organ slice
Structure Level Pattern Image Note
TS28: telencephalon Present 9a
Specimen 9b: postnatal day 12; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 9b
Specimen 9c: postnatal day 15; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: brain Present 9c
TS28: cerebellum Purkinje cell layer Present 9c
Specimen 9d: postnatal day 15; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: heart Present 9d left Expression was relatively uniform.
TS28: cardiac muscle tissue Present 9d left
Specimen 9e: postnatal day 15; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: uterine artery Present 9e left
TS28: uterus Present 9e left Expression was relatively uniform.
Specimen 9f: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: retina Present 9f left
Specimen 9g: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: adrenal gland Present 9g left
Specimen 9h: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Note: organ slice
Structure Level Pattern Image Note
TS28: liver Present 9h left
Specimen 9i: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: spinal cord Present 9i left
Specimen 9j: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Note: organ slice
Structure Level Pattern Image Note
TS28: renal cortex Present 9j
TS28: renal medulla Strong 9j
Specimen 10a: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: hyaline cartilage Present 10a
TS28: trachea epithelium Present 10a
Specimen 10b: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: bronchiole epithelium Strong 10b
TS28: bronchus epithelium Strong 10b
TS28: bronchial artery Present 10b Expressed in vascular smooth muscle cells.
Specimen 10c: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: alveolus epithelium Present Non-Uniform 10c Mainly expressed in cells resembling type II pneumocytes.
Specimen 10d: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: stomach mucosa Present 10d
TS28: stomach muscularis externa Present 10d
TS28: stomach fundus gastric gland Present 10d Expressed in cells at the base.
Specimen 10e: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: stomach epithelium Present 10e
TS28: stomach fundus gastric gland Present 10e Expressed in cells at the base.
Specimen 10f: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: colon epithelium Present 10f Expressed in surface enterocytes.
Specimen 10g: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present 10g Expressed in the epithelium.
TS28: epidermis Present Regionally restricted 10g Expressed in the basal layer of keratinocytes.
Specimen 10h: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: renal papilla Strong 10h
Specimen 10i: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: loop of Henle of renal medulla Strong 10i
Specimen 10j: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: juxtaglomerular complex Present 10j Expressed in vascular smooth muscle cells.
TS28: renal tubule epithelium Present Regionally restricted 10j Expressed in cells in the distal tubules.
Specimen 10k: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: juxtaglomerular complex Present 10k Expressed in vascular smooth muscle cells.
Specimen 10l: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: remnant of Rathke's pouch Present 10l Expressed in Rathke's cleft cysts.
Specimen 10m: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: remnant of Rathke's pouch Present Regionally restricted 10m Expressed in ciliated epithelium of Rathke's cleft cysts.
Specimen 10n: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 10n
Specimen 10o: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 10o
Specimen 10p: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: telencephalon Present 10p Expressed in neurons, but not all neuronal populations were positive.
Specimen 10q: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: diaphragm Present Regionally restricted 10q Expressed in muscle fibers.
Specimen 10r: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: mesenteric artery Present Regionally restricted 10r Expressed in vascular smooth muscle cells.
Specimen 10s: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: mesenteric artery Present Regionally restricted 10s Expressed in vascular smooth muscle cells.
Specimen 10t: postnatal month 4; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: aorta Present Regionally restricted 10t Expressed in vascular smooth muscle cells.
Specimen 11a: postnatal day 20; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Uniform 11a upper Expressed in all muscle fibers, with a band of intensely stained spots stretching across the approximate middle of the muscle.
Specimen 11b: postnatal day 20; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 11b Expressed in all muscle fibers, with a band of intensely stained spots stretching across the approximate middle of the muscle
Specimen 11c: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 11c Expressed in all muscle fibers, with a band of intensely stained spots stretching across the approximate middle of the muscle
Specimen 11d: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 11d Expressed in all muscle fibers, with a band of intensely stained spots stretching across the approximate middle of the muscle
Specimen 11e: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Note: free-floating section
Structure Level Pattern Image Note
TS28: skeletal muscle Present Regionally restricted 11e Expressed in the postsynaptic area.
Specimen 11f: postnatal day 60; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Present Regionally restricted 11f Expressed in the postsynaptic area.
Specimen 12g/h: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Note: Triple labeled: black - Pdgfa; red - Acta2 (assay MGI:6715117); green - Pdgfa (assay MGI:6715116).
Structure Level Pattern Image Note
TS28: blood vessel smooth muscle Present 12h , 12g
Specimen 12i: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: liver Present 12i Expressed in megakaryocytes.
Specimen 12j: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: liver Present 12j Expressed in megakaryocytes.
Specimen 12k: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: liver Present 12k Expressed in megakaryocytes.
Specimen 12l: postnatal day 5; Pdgfatm1Vlcg/Pdgfa+ (more )
Structure Level Pattern Image Note
TS28: liver Present 12l Expressed in megakaryocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory