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Gene Expression Data
Assay Details
Assay
Reference: J:142399 Tamboli IY, et al., Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis. J Neurosci. 2008 Nov 12;28(46):12097-106
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6712430
Gene symbol: Apoe
Gene name: apolipoprotein E
Antibody: anti-apo E
Results
Specimen 4B ctrl: postnatal; Psen1tm1Vln/Psen1tm1Vln (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4B ctrl bottom , 4B ctrl top Staining is homogeneous in the cytoplasm of the neurons.
Specimen 4B PS1n-/-: postnatal; Psen1tm1Vln/Psen1tm1Vln, Tg(Thy1-cre)1Vln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4B PS1n-/- top , 4B PS1n-/- bottom In this mutant expression is decreased in the cytoplasm but is strong at the plasma membrane.
Specimen 4C ctrl: postnatal; Psen1tm1Vln/Psen1tm1Vln (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4C ctrl bottom , 4C ctrl top Staining is homogeneous in the cytoplasm of the neurons.
Specimen 4C PS1n-/-: postnatal; Psen1tm1Vln/Psen1tm1Vln, Tg(Thy1-cre)1Vln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 4C PS1n-/- top , 4C PS1n-/- bottom In this mutant expression is decreased in the cytoplasm but is strong at the plasma membrane.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory