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Gene Expression Data
Assay Details
Assay
Reference: J:293298 Zhang M, et al., Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711378
Gene symbol: Krt15
Gene name: keratin 15
Antibody: anti-K15
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A WT E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis Present Regionally restricted 2A1-1 Expressed in the basal stem cells.

Specimen 2A KO E15.5: embryonic day 15.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: epidermis Present Regionally restricted 2A1-2 Expressed in the basal stem cells.

Specimen 2A WT E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 2A2-1 Expressed in the basal stem cells.

Specimen 2A KO E17.5: embryonic day 17.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: epidermis Trace Regionally restricted 2A2-2 There were few positive cells in the basal layer.

Specimen 2A WT P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis basal layer Present 2A3-1 Expressed in the basal stem cells.

Specimen 2A KO P1: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epidermis basal layer Trace 2A3-2 There were few positive cells in the basal layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory